Synthesis and biological activity of acetylacetone thiosemicarbazone and their metallic complexes.

dc.contributor.authorKumar, Sandeep
dc.contributor.authorKumar, Nitin
dc.date.accessioned2014-07-22T04:56:44Z
dc.date.available2014-07-22T04:56:44Z
dc.date.issued2013-03
dc.description.abstractIn present work, Ligand acetylacetone thiosemicarbazone and their 11 complexes of the type ML2X2, ML2X’, where M = Cu(II), Cd(II), Co(II), Zn(II), Hg(II); L = acetylacetone thiosemicarbazone; X = Cl, NO3 or CH3COO; X’ = SO4 have been synthesized and characterized with the help of molar conductance, magnetic susceptibility measurements, infra-red and ultra-violet spectroscopy. The spectral data revealed that the thiosemicarbazone act as bidentate ligand, making use of thionic sulphur and the azomethine nitrogen atom for co-ordination to the central metal atom. All the compounds have been screened for their antibacterial activity against Gram positive bacteria Staphylococcus aureus, Staphylococcus epidermidis and Gram negative bacteria Escherichia coli and Pseudomonas aeruginosa. Some of complexes exhibited appreciable activity.en_US
dc.identifier.citationKumar Sandeep, Kumar Nitin. Synthesis and biological activity of acetylacetone thiosemicarbazone and their metallic complexes. International Current Pharmaceutical Journal. 2013 Mar 2(4): 88-91.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/152969
dc.language.isoenen_US
dc.source.urihttps://www.icpjonline.com/documents/Vol2Issue4/02Abstract.htmen_US
dc.subjectThiosemicarbazoneen_US
dc.subjectthiosemicarbazone complexesen_US
dc.subjectmetallic complexesen_US
dc.subjectcharacterizationen_US
dc.subjectantibacterial activity and spectral studiesen_US
dc.titleSynthesis and biological activity of acetylacetone thiosemicarbazone and their metallic complexes.en_US
dc.typeArticleen_US
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