Healing of Extracted Socket after Surgical Removal of Impacted Mandibular 3rd Molar: A Comparison of PRP VS PRP with Bone Graft

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dc.contributor.authorBokhari, Ken_US
dc.contributor.authorNada, Aen_US
dc.contributor.authorJawaher, Aen_US
dc.contributor.authorFalah, Hen_US
dc.contributor.authorIsmail, Aen_US
dc.date.accessioned2019-12-06T09:21:06Z
dc.date.available2019-12-06T09:21:06Z
dc.date.issued2018-09
dc.description.abstractBackground: Platelet-rich plasma (PRP) is an autologous concentration of human platelets in a small volume of plasma. Because it is a concentration of platelets, it is also a concentration of the 7 fundamental protein growth factors proved to be actively secreted by platelets to initiate all wound healing. PRP contributes to better healing of soft tissues and bone and is a visible means of growth factor delivery. Aims & Objectives: a) To compare osteo -inductive capacity following surgical removal of impacted mandibular 3rd molar teeth b) to compare the difference in osteoinduction between PRP vs PRP + Bone Graft, c) Establish the potential benefits of these biomaterials in the regeneration of post-extraction alveolar bone. Methods:This is a prospective, randomized clinical trial involving 15 patients (split arch – 30 impacted molar teeth) who visited KKUCOD (Alsamer campus) for surgical removal of symptomatic impactedmandibular third molars. The study was conducted following due clearance from ethical and research committee of the institution (SRC/ETH/2016-17/004). The inclusion criteria included: Female patients aged between 18 and 45, b) Impacted mandibular third molar with similar anatomical position, and similar difficulty index.c Patient informed consent to carry out the intervention and for inclusion in the study. d) No allergies to medicines, non –smokers, non-alcoholics, no drug allergy and patients not under oral contraceptives. Results: The results are compiled as tables for different groups with percentage of bone formation at the end of week 1,3, 6 and at the end of 3rd months. There is not much difference in osteoinduction with the addition of PRP alone when compared to control side. However, addition of graft with PRP definitely enhances osteoinduction and makes a significant contribution in neo bone regeneration Conclusion: 1. PRP contributes significantly to osteogenesis when mixed with bone graft. 2. Healing is better when extracted sockets are supplemented with PRP. 3. There is no incidence of allergic reaction with the use of allogeneic bone grafts.en_US
dc.identifier.affiliationsProfessor, Department of Dentistry, Government Medical College, Dimrapal, Jagadalpur, Chattisgarh,Indiaen_US
dc.identifier.affiliationsNada Aied, Jawaher Assiri, Falah Huzzaim, Ismail Abdullah. Intern, College of Dentistry, King Khalid University, KSAen_US
dc.identifier.citationBokhari K, Nada A, Jawaher A, Falah H, Ismail A. A Study of Serum Ferritin in Acute Myocardial Infarction: A Case Control Study in BLDE (Deemed To Be University), Shri BM Patil Medical College, Hospital and Research Centre Vijayapura. Annals of International medical and Dental Research. 2018 Sep; 4(5): 36-41en_US
dc.identifier.issn2395-2822
dc.identifier.issn2395-2814
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/188237
dc.languageenen_US
dc.publisherSociety for Health Care & Research Developmenten_US
dc.relation.issuenumber5en_US
dc.relation.volume4en_US
dc.source.urihttps://doi.org/10.21276/aimdr.2018.4.5.DE10en_US
dc.titleHealing of Extracted Socket after Surgical Removal of Impacted Mandibular 3rd Molar: A Comparison of PRP VS PRP with Bone Graften_US
dc.typeJournal Articleen_US
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