A randomized placebo controlled trial of Inolter (herbal product) in the treatment of type 2 diabetes.

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dc.contributor.authorAgrawal, R Pen_US
dc.contributor.authorSharma, Aradhanaen_US
dc.contributor.authorDua, A Sen_US
dc.contributor.authorChandershekhar,en_US
dc.contributor.authorKochar, D Ken_US
dc.contributor.authorKothari, R Pen_US
dc.date.accessioned2002-03-02en_US
dc.date.accessioned2009-05-31T01:05:05Z
dc.date.available2002-03-02en_US
dc.date.available2009-05-31T01:05:05Z
dc.date.issued2002-03-02en_US
dc.description.abstractOBJECTIVE: To evaluate the safety and effectiveness of Inolter in achieving glycemic control and changes in lipid profile of newly diagnosed type 2 diabetics. MATERIAL AND METHODS: Study design: A randomized, placebo-controlled double blind. Sixty newly diagnosed patients of type-2 diabetes were randomized. Of these, 30 were put on Inolter monotherapy and 30 patients on placebo. Efficacy of Inolter was determined by observing glycemic control by estimating glycosylated haemoglobin (HbA1c) and fasting blood sugar (FBS), alteration of lipid profile by serum cholesterol, LDL, VLDL, HDL and triglycerides. STATISTICAL METHODS: Student's unpaired 't' test. RESULTS: Patients compliance was satisfactory and no adverse effects were observed. Better hypoglycemic effect was observed with Inolter both respect to fasting blood sugar (mean 65.4 +/- 63.72 mg/dl) compared to placebo (mean 26.45 +/- 38.3 mg/dl) (p < 0.001). The mean change, with Inolter, in serum cholesterol (21.33 +/- 26.05 mg/dl), serum triglyceride (30.36 +/- 32.62 mg/dl), VLDL (8.85 +/- 3.25 mg/dl), LDL (10.00 +/- 4.48 mg/dl) and HDL (-2.33 +/- 5.66 mg/dl) was also significantly different (p < 0.001) from those given placebo, where it was 15.7 +/- 20.14 mg/dl, 8.70 +/- 13.24, 0.10 +/- 4.10 mg/dl, -0.70 +/- 4.58 mg/dl and 0.65 +/- 0.00 mg/dl, respectively. CONCLUSION: Inolter appears to be an useful adjunctive therapy to exercise and diet control in newly diagnosed type 2 diabetes mellitus.en_US
dc.description.affiliationDepartment of Medicine, SP Medical College, Bikaner.en_US
dc.identifier.citationAgrawal RP, Sharma A, Dua AS, Chandershekhar , Kochar DK, Kothari RP. A randomized placebo controlled trial of Inolter (herbal product) in the treatment of type 2 diabetes. Journal of the Association of Physicians of India. 2002 Mar; 50(): 391-3en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/91866
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshCholesterol --blooden_US
dc.subject.meshDiabetes Mellitus, Type 2 --drug therapyen_US
dc.subject.meshDouble-Blind Methoden_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshHypoglycemic Agents --therapeutic useen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPatient Complianceen_US
dc.subject.meshPhytotherapyen_US
dc.subject.meshPlant Preparations --therapeutic useen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleA randomized placebo controlled trial of Inolter (herbal product) in the treatment of type 2 diabetes.en_US
dc.typeClinical Trialen_US
dc.typeJournal Articleen_US
dc.typeRandomized Controlled Trialen_US
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