A prospective study of demographic profile, risk factors and pregnancy outcome in Hepatitis B and Hepatitis C virus positive pregnant women in a tertiary care centre

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dc.contributor.authorSharma, Artien_US
dc.contributor.authorAgarwal, Shubhraen_US
dc.contributor.authorBajpai, Garimaen_US
dc.contributor.authorSingh, Anupriyaen_US
dc.contributor.authorAgarwal, Nikitaen_US
dc.contributor.authorMishra, Shwetaen_US
dc.date.accessioned2020-10-16T08:05:05Z
dc.date.available2020-10-16T08:05:05Z
dc.date.issued2020-06
dc.description.abstractBackground: Viral hepatitis is the most common liver disease in pregnancy and is also the most common cause of jaundice in pregnancy in tropical countries. Risk factors for transmission are intravenous drug abuse, surgical and dental procedures done without adequate sterilization of instruments, sexual route etc. Early diagnosis and management can prevent maternal and fetal complications. This study was done to evaluate the frequency, risk factors and pregnancy outcome in hepatitis B virus (HBV) and hepatitis C virus (HCV) positive antenatal women.Methods: This case control study was conducted in Teerthankar Mahaveer Medical College and Research Centre, Moradabad, Uttar Pradesh, India from January 2017 to June 2018 on total 2511 pregnant women. The serum samples were checked for presence of hepatitis B surface antigen (HBsAg) and presence of IgG antibodies to HCV. Analysis of sociodemographic profile, risk factors and pregnancy outcome were done in all HBV and HCV positive women.Results: Out of 2511 pregnant women, 292 were tested positive for hepatitis. Maximum number of women were in the age group of 21-30 years. Most of the seropositive women were multipara. Frequency of positivity was maximum for HCV (67.1%). The risk factors for transmission in study population were intravenous drug abuse, blood transfusion, history of surgery and tattooing.Conclusions: Hepatitis infection rate is increasing. Universal screening for HBV and HCV can be recommended in pregnant women in developing countries. Education and awareness of public and health care workers can reduce the risk of transmission.en_US
dc.identifier.affiliationsDepartment of Obstetrics and Gynecology, Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, Uttarakhand, Indiaen_US
dc.identifier.affiliationsDepartment of Obstetrics and Gynecology, Teerthankar Mahaveer Medical College and Research Centre, Moradabad, Uttar Pradesh, Indiaen_US
dc.identifier.citationSharma Arti, Agarwal Shubhra, Bajpai Garima, Singh Anupriya, Agarwal Nikita, Mishra Shweta. A prospective study of demographic profile, risk factors and pregnancy outcome in Hepatitis B and Hepatitis C virus positive pregnant women in a tertiary care centre. International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2020 Jun; 9(6): 2393-2396en_US
dc.identifier.issn2320-1770
dc.identifier.issn2320-1789
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/207758
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber6en_US
dc.relation.volume9en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-1770.ijrcog20202317en_US
dc.subjectAntenatal womenen_US
dc.subjectHepatitis B virusen_US
dc.subjectHepatitis C virusen_US
dc.subjectTransmissionen_US
dc.titleA prospective study of demographic profile, risk factors and pregnancy outcome in Hepatitis B and Hepatitis C virus positive pregnant women in a tertiary care centreen_US
dc.typeJournal Articleen_US
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