Dietary factors in pathogenesis of gallstone disease in southern India--a hospital-based case-control study.

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dc.contributor.authorJayanthi, Ven_US
dc.contributor.authorAnand, Len_US
dc.contributor.authorAshok, Len_US
dc.contributor.authorSrinivasan, Vijayaen_US
dc.date.accessioned2005-05-26en_US
dc.date.accessioned2009-05-29T03:04:53Z
dc.date.available2005-05-26en_US
dc.date.available2009-05-29T03:04:53Z
dc.date.issued2005-05-26en_US
dc.description.abstractBACKGROUND: Pigment or mixed gallstones are common in southern India. The etiology is not established. Known risk factors include an obese, diabetic female and a nonsmoker male. AIM: To determine the association of dietary factors with mixed/pigment gallstones amongst southern Indian patients. METHODS: Diet details were obtained from 346 patients (178 women) with gallstones and an equal number of healthy controls who were age- and sex-matched attendants of the patients, sharing similar socioeconomic and demographic characteristics, with normal abdominal ultrasonogram. Data recorded included the number of daily meals, nature of cereal used, vegetarianism, oil consumed per month, sugar consumption per day, tamarind (Garcinia camborginia ) usage per week, and per-day beverage consumption. RESULTS: There was no difference between cases and controls in consumption of non-vegetarian food, type of cereal, average oil and sugar consumption, and type of beverage consumed (tea/coffee/milk/combination). Individuals with BMI> 22 were at higher risk to develop gallstones (OR 1.49; 95% CI 1.09, 2.04; p=0.01). There was significant risk of gallstone formation with the use of tamarind when consumed > 3 times a week (OR 1.76; 95% CI 1.05, 2.96; p=0.03). Higher BMI and tamarind use were significant risk factors even on multivariate logistic regression analysis (p=0.02). CONCLUSION: Higher BMI and use of tamarind, a common ingredient of diet in southern India, are risk factors in the formation of gallstones in southern India.en_US
dc.description.affiliationDepartment of Gastroenterology, Stanley Medical College Hospital, Chennai, India. drjayant1@vsnl.comen_US
dc.identifier.citationJayanthi V, Anand L, Ashok L, Srinivasan V. Dietary factors in pathogenesis of gallstone disease in southern India--a hospital-based case-control study. Indian Journal of Gastroenterology. 2005 May-Jun; 24(3): 97-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/64911
dc.language.isoengen_US
dc.source.urihttps://www.indianjgastro.comen_US
dc.subject.meshBody Mass Indexen_US
dc.subject.meshCase-Control Studiesen_US
dc.subject.meshDieten_US
dc.subject.meshDiet Recordsen_US
dc.subject.meshFemaleen_US
dc.subject.meshGallstones --epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshLogistic Modelsen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshTamarindusen_US
dc.titleDietary factors in pathogenesis of gallstone disease in southern India--a hospital-based case-control study.en_US
dc.typeJournal Articleen_US
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