Anti-malarial activity of Eclipta alba against Plasmodium berghei infection in mice.

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dc.contributor.authorBapna, Sarojen_US
dc.contributor.authorAdsule, Shashanken_US
dc.contributor.authorShirshat Mahendra, Sen_US
dc.contributor.authorJadhav, Suryajien_US
dc.contributor.authorPatil, L Sen_US
dc.contributor.authorDeshmukh, R Aen_US
dc.date.accessioned2007-06-15en_US
dc.date.accessioned2009-06-01T18:24:19Z
dc.date.available2007-06-15en_US
dc.date.available2009-06-01T18:24:19Z
dc.date.issued2007-06-15en_US
dc.description.abstractThe anti-malarial activity of Eclipta alba leaves extract was evaluated against Plasmodium'berghei ANKA strain in mice. A standard inoculum of 1 x 10(6) infected erythrocytes was used. The methanolic leaf extract (250-750 mg/kg) produced a dose-dependant chemosupression or schizontocidal effect during early and established infection and high mean survival time (m.s.t.) values particularly in the group administered 750 mg/kg/day of extract. The plant extract also exhibited repository activity. The results of the preliminary studies carried out with E. alba are encouraging, which can be exploited in malaria therapy.en_US
dc.description.affiliationHaffkine Institute for Training Research and Testing, Parel, Mumbai.en_US
dc.identifier.citationBapna S, Adsule S, Shirshat Mahendra S, Jadhav S, Patil LS, Deshmukh RA. Anti-malarial activity of Eclipta alba against Plasmodium berghei infection in mice. Journal of Communicable Diseases. 2007 Jun; 39(2): 91-4en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/112199
dc.language.isoengen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntimalarials --therapeutic useen_US
dc.subject.meshDisease Models, Animalen_US
dc.subject.meshEclipta --chemistryen_US
dc.subject.meshHumansen_US
dc.subject.meshMalaria --drug therapyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiceen_US
dc.subject.meshParasitic Sensitivity Testsen_US
dc.subject.meshPhytotherapyen_US
dc.subject.meshPlant Extracts --therapeutic useen_US
dc.subject.meshPlasmodium berghei --drug effectsen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleAnti-malarial activity of Eclipta alba against Plasmodium berghei infection in mice.en_US
dc.typeJournal Articleen_US
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