Second digit and fourth digit ratio – an adjunct tool to predict obstructive sleep apnea.
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Date
2014-07
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Abstract
Obstructive sleep apnea (OSA) is a sleep related breathing disorder associated with high morbidity and
mortality. Digit ratio (2D:4D) a sexually dimorphic trait is a putative indicator of prenatal testosterone
exposure and adult testosterone level. Present study aimed at investigating the correlation between 2D:4D
ratio and OSA based on the study conducted on 290 volunteered participants of both the sexes in the age
range of 20-45 years. A significant negative correlation was observed for 2D:4D with OSA related parameters
specifically Berlin score, Epworth score and certain key anthropometric measurements, neck circumference
(NC) and waist-hip ratio (WHR). The study thus showed that lower 2D:4D ratio, increases risk of developing
OSA and hence it can be used as an adjunct tool in the prediction of OSA.
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Srihari R, Mathangi K, Sriteja Y, Remya K J, Mathangi D C, Shyamala R. Second digit and fourth digit ratio – an adjunct tool to predict obstructive sleep apnea. Indian Journal of Physiology and Pharmacology. 2014 Jul-Sept; 58(3): 292-295.