Current approach to diagnosis of inflammatory myopathies: Clinical features and myositis antibody profiles

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dc.contributor.authorShobha, Ven_US
dc.contributor.authorRajasekhar, L.en_US
dc.date.accessioned2023-08-10T07:32:36Z
dc.date.available2023-08-10T07:32:36Z
dc.date.issued2022-05
dc.description.abstractDiagnosis of inflammatory myositis has been made easier with the availability of commercial assays for myositis-specific and myositis-associated antibodies. Clinico-serological association studies have permitted a better definition of clinical subsets. Myositis-specific auto-antibodies are highly specific and non-overlapping, whereas myositis-associated antibodies are those seen also in other connective tissue disorders such as systemic lupus erythematosus, primary Sjogren's syndrome, and idiopathic pulmonary auto-immune fibrosis. Their value is pronounced when clinical features are subtle or non-specific or when the muscle is not the primary organ involved. Overall, the muscle-specific and myositis-associated antibodies have changed the landscape in terms of diagnostic utility, prognostication, and the approach to organ-specific evaluation and management of idiopathic inflammatory myopathies (IIMs).en_US
dc.identifier.affiliationsDepartment of Clinical Immunology and Rheumatology, St John's Medical College Hospital, Bangalore, Karnataka, Indiaen_US
dc.identifier.affiliationsDepartment of Clinical Immunology and Rheumatology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, Indiaen_US
dc.identifier.citationShobha V, Rajasekhar L.. Current approach to diagnosis of inflammatory myopathies: Clinical features and myositis antibody profiles. Indian Journal of Pathology & Microbiology. 2022 May; 65(1): 252-258en_US
dc.identifier.issn0377-4929
dc.identifier.issn0974-5130
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/223287
dc.languageenen_US
dc.publisherWolters Kluwer - Medknowen_US
dc.relation.issuenumber1en_US
dc.relation.volume65en_US
dc.source.urihttps://doi.org/10.4103/ijpm.ijpm_1082_21en_US
dc.subjectClinical featuresen_US
dc.subjectinflammatory myopathyen_US
dc.subjectmyositis profileen_US
dc.titleCurrent approach to diagnosis of inflammatory myopathies: Clinical features and myositis antibody profilesen_US
dc.typeJournal Articleen_US
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