Correlation between prostate specific antigen and prostate volume with disease symptom severity assessed by international prostate symptom score

Simple item page
dc.contributor.authorSalvi, N.en_US
dc.contributor.authorVyas, S.en_US
dc.contributor.authorBhatt, R.en_US
dc.contributor.authorPatel, P.en_US
dc.contributor.authorPatel, S.en_US
dc.contributor.authorAgarwal, C.en_US
dc.date.accessioned2024-09-24T09:14:56Z
dc.date.available2024-09-24T09:14:56Z
dc.date.issued2023-04
dc.description.abstractBackground: Benign prostatic hyperplasia (BPH) is clinically defined as prostate adenoma, resulting in bladder outlet obstruction (BOO), which may eventually harm the bladder and even kidneys. For differential diagnosis of male LUTS, uroflowmetry can be used together with non-invasive ultrasound to ascertain the flow rate and IPP. PSA is also an important indicator for differential diagnosis. International prostate symptoms score (IPSS) is used to assess the severity of the symptoms for clinical BPH. There is also a recommendation to consider the quality of life (QoL) index, where a QoL score of ?3 is considered as worrisome. Methods: This was a retro-prospective study based on secondary and primary data collection and analysis, pertaining to BPH patients who visited the study site previously as well as those who are coming for regular follow-up since 2019. Patient enrolment was done at a teaching hospital Shree Krishna Hospital affiliated to the Pramukh Swami Medical College, Bhaikaka University, Karamsad. About 100 patients presenting with lower urinary tract symptoms (LUTS) and histo-pathologically proven cases of BPH were enrolled to pursue research objectives. All patients were followed up to a period of 3-months after initiating the treatment and disease severity through IPSS and quality of life upon completion of treatment were also assessed. Results: PSA is also an important indicator for differential diagnosis, which is generally less than 1 ?g/l in patients in absence of clinically confirmed BPH. In our study, mean prostate volume was reported to be 43.46±19.35 cc. A positive correlation was observed between prostate volume and serum PSA with disease severity. Conclusions: Our study evaluated the IPSS to predict the disease severity and correlated it with quality of life, prostate volume and serum PSA. Our findings were in line with currently available evidences, and suggested that QoL, prostate volume and serum PSA are better predictors of disease severity, IPSS.en_US
dc.identifier.affiliationsDepartment of Surgery, Pramukhswami Medical College, Karamsad, Anand, Gujarat, Indiaen_US
dc.identifier.affiliationsDepartment of Surgery, Pramukhswami Medical College, Karamsad, Anand, Gujarat, Indiaen_US
dc.identifier.affiliationsDepartment of Surgery, Pramukhswami Medical College, Karamsad, Anand, Gujarat, Indiaen_US
dc.identifier.affiliationsDepartment of Surgery, Pramukhswami Medical College, Karamsad, Anand, Gujarat, Indiaen_US
dc.identifier.affiliationsDepartment of Surgery, Pramukhswami Medical College, Karamsad, Anand, Gujarat, Indiaen_US
dc.identifier.affiliationsDepartment of Surgery, Pramukhswami Medical College, Karamsad, Anand, Gujarat, Indiaen_US
dc.identifier.citationSalvi N., Vyas S., Bhatt R., Patel P., Patel S., Agarwal C.. Correlation between prostate specific antigen and prostate volume with disease symptom severity assessed by international prostate symptom score. International Journal of Research in Medical Sciences. 2023 Apr; 11(4): 1228-1233en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/233105
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber4en_US
dc.relation.volume11en_US
dc.source.urihttps://doi.org/10.18203/2320-6012.ijrms20230866en_US
dc.subjectBPHen_US
dc.subjectIPSSen_US
dc.subjectProstateen_US
dc.subjectProstate volumeen_US
dc.subjectPSAen_US
dc.titleCorrelation between prostate specific antigen and prostate volume with disease symptom severity assessed by international prostate symptom scoreen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
ijrms2023v11n4p1228.pdf
Size:
491.13 KB
Format:
Adobe Portable Document Format
Download
Collections
International Journal of Research in Medical Sciences