Nephrogenic systemic fibrosis following acute kidney injury and exposure to gadolinium.
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Date
2010-01
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Abstract
Nephrogenic systemic fibrosis (NSF) is a scleroderma-like systemic fibrosing condition of unknown etiology described in patients with renal insufficiency. Gadolinium exposure has been strongly associated with the development of NSF though the mechanism of such injury is not known. There are only few reported cases of NSF in the setting of acute renal failure and fewer reported cases where skin lesions developed after kidney function had returned to normal. We report a case of NSF in a young Hispanic woman with lupus nephritis but normal creatinine, who received gadolinium during a brief episode of prerenal acute kidney injury not requiring dialysis, secondary to sepsis.
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Keywords
Acute renal failure, gadolinium, nephrogenic systemic fibrosis, normal creatinine, normal kidney function, prerenal acute renal failure
Citation
Bhaskaran Archana, Kashyap Purna, Kelly Brent, Ghera Princy. Nephrogenic systemic fibrosis following acute kidney injury and exposure to gadolinium. Indian Journal of Medical Sciences. 2010 Jan; 64(1) 33-36.