Malignant melanotic nerve sheath tumour of chest wall: a rare and diagnostically challenging case

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dc.contributor.authorQayoom, Sen_US
dc.contributor.authorGoel, Den_US
dc.contributor.authorJaiswal, Ren_US
dc.contributor.authorAkhtar, N.en_US
dc.date.accessioned2025-05-12T07:25:03Z
dc.date.available2025-05-12T07:25:03Z
dc.date.issued2024-11
dc.description.abstractMalignant melanotic nerve sheath tumour (MMNST), previously known as melanotic schwannomas (MS) comprise less than 1% of nerve sheath tumors and around 200 cases have been reported in the literature. According to the WHO 5th edition, it is now classified as malignant neoplasm due to its local recurrence rate and metastatic risk. Although it is classified as malignant, the histopathological criteria for malignancy and prognostic factors remain ill-defined due to its rarity. It also poses a diagnostic challenge as it resembles closely other benign as well as malignant melanin producing tumors. We report here a case of 33 year old female who presented with chest wall swelling and was diagnosed as MS (now classified as MMNST) on histopathology and immunohistochemistry. This case highlights the diagnostic difficulties and the importance of careful histological evaluation and long-term follow-up.en_US
dc.identifier.affiliationsDepartment of Pathology, King George抯 Medical University, Lucknow, UP, Indiaen_US
dc.identifier.affiliationsDepartment of Pathology, King George抯 Medical University, Lucknow, UP, Indiaen_US
dc.identifier.affiliationsDepartment of Pathology, King George抯 Medical University, Lucknow, UP, Indiaen_US
dc.identifier.affiliationsDepartment of Surgical Oncology, King George抯 Medical University, Lucknow, UP, Indiaen_US
dc.identifier.citationQayoom S, Goel D, Jaiswal R, Akhtar N.. Malignant melanotic nerve sheath tumour of chest wall: a rare and diagnostically challenging case . International Journal of Research in Medical Sciences. 2024 Nov; 12(11): 4356-4359en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/246681
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber11en_US
dc.relation.volume12en_US
dc.source.urihttps://doi.org/10.18203/2320-6012.ijrms20243404en_US
dc.subjectMelanoticen_US
dc.subjectNerve sheath tumouren_US
dc.subjectBRAFV600Een_US
dc.titleMalignant melanotic nerve sheath tumour of chest wall: a rare and diagnostically challenging caseen_US
dc.typeJournal Articleen_US
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