Extramedullary hematopoiesis in ovary: a rare presentation of CML

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dc.contributor.authorAgarwal, Akritien_US
dc.contributor.authorGokhale, Asha Niranjanen_US
dc.date.accessioned2020-10-16T07:55:22Z
dc.date.available2020-10-16T07:55:22Z
dc.date.issued2019-04
dc.description.abstractExtramedullary hematopoiesis (EMH) is a rare phenomenon, and represents infiltration and proliferation of myeloid, erythroid, and megakaryocytic cells in non-bone marrow sites. Extramedullary hematopoiesis (EMH) is normal during fetal life, but after birth, the presence of EMH is considered to be abnormal.  EMH has been associated with CML (chronic myeloid leukaemia). Lymph node is the most common site of involvement, other sites being the abdomen (liver, spleen) and thorax (bone, mediastinum) but very rarely in the gynecological tract. Here authors report a case of a 20-year young female, a known case of CML who presented with abdominal pain with hemoperitonium, with negative urine pregnancy test. Initially hemorrhagic corpus luteal cyst was thought to be the cause of hemoperitonium and patient was taken for surgery wherein histopathology confirmed the diagnosis of extra medullary hematopoiesis of ovary. Women with CML when presents with hemoperitoneum, extramedullary hematopoiesis should be a differential diagnosis apart from rupture ectopic and other causes of spontaneous hemoperitoneum.  Patient was started on imatinib after diagnosis and is doing well.en_US
dc.identifier.affiliationsDepartment of Obstetrics and Gynecology, Deenanath Mangeshkar Hospital and Research Centre, Pune, Maharashtra, Indiaen_US
dc.identifier.citationAgarwal Akriti, Gokhale Asha Niranjan. Extramedullary hematopoiesis in ovary: a rare presentation of CML. International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2019 Apr; 8(4): 1689-1691en_US
dc.identifier.issn2320-1770
dc.identifier.issn2320-1789
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/206666
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber4en_US
dc.relation.volume8en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-1770.ijrcog20191244en_US
dc.subjectChronic myeloid leukaemiaen_US
dc.subjectCorpus luteal cysten_US
dc.subjectExtramedullary hematopoisisen_US
dc.subjectHaemoperitoneumen_US
dc.titleExtramedullary hematopoiesis in ovary: a rare presentation of CMLen_US
dc.typeJournal Articleen_US
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