Quantitative analysis of antigen specific IgE in tears in comparison to serum samples.

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dc.contributor.authorOno, Tetsuyaen_US
dc.contributor.authorKawamura, Masahideen_US
dc.contributor.authorArao, Shinsukeen_US
dc.contributor.authorSahashi, Norioen_US
dc.contributor.authorNariuchi, Hideoen_US
dc.date.accessioned2009-05-27T17:09:57Z
dc.date.available2009-05-27T17:09:57Z
dc.date.issued2005-12-29en_US
dc.descriptionPublished by the Allergy and Immunology Society of Thailand.en_US
dc.description.abstractWe determined pollen specific IgE in tears and compared these results to the concentration of specific IgE in serum samples. We obtained tears (using Schirmer strips) and serum samples from subjects with Japanese cedar (Cryptomeria japonica) pollinosis, and tested for C. japonica pollen specific IgE using a quantitative ELISA. Time kinetic analyses through the pollen season showed that specific IgE levels in tears were found to increase earlier than those in sera and reached their maximum at the end of or after the pollen season, from March to early June. In the C. japonica pollen free season, July to December, the specific IgE levels in tears decreased, although the serum levels remained relatively high. These results indicate that the quantitative assay for specific IgE in tears might be useful to identify specific eye allergens.en_US
dc.description.affiliationResearch and Development Department, Mitsubishi Kagaku latron, Inc., Chiba, Japan. ono.tetsuya@mk.mk-iatron.co.jpen_US
dc.identifier.citationOno T, Kawamura M, Arao S, Sahashi N, Nariuchi H. Quantitative analysis of antigen specific IgE in tears in comparison to serum samples. Asian Pacific Journal of Allergy and Immunology. 2005 Jun-Sep; 23(2-3): 93-100en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/36594
dc.language.isoengen_US
dc.subject.meshAdulten_US
dc.subject.meshAntigen-Antibody Reactions --immunologyen_US
dc.subject.meshAntigens, Plant --blooden_US
dc.subject.meshCryptomeria --immunologyen_US
dc.subject.meshEnzyme-Linked Immunosorbent Assayen_US
dc.subject.meshEpitopes --immunologyen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunoglobulin E --blooden_US
dc.subject.meshJapan --epidemiologyen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPollen --classificationen_US
dc.subject.meshRhinitis, Allergic, Seasonal --immunologyen_US
dc.subject.meshSeasonsen_US
dc.subject.meshTears --immunologyen_US
dc.titleQuantitative analysis of antigen specific IgE in tears in comparison to serum samples.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
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