Traditional complementary and alternative medicine (TCAM) for diabetic foot ulcer management: A systematic review

dc.contributor.authorKumar, Sumanen_US
dc.contributor.authorBharali, Alakeshen_US
dc.contributor.authorSarma, Himangshuen_US
dc.contributor.authorKushari, Susankaren_US
dc.contributor.authorGam, Sameeranen_US
dc.contributor.authorHazarika, Iswaren_US
dc.contributor.authorPrasad, Satyendra K.en_US
dc.contributor.authorLaloo, Damikien_US
dc.date.accessioned2024-11-30T08:13:06Z
dc.date.available2024-11-30T08:13:06Z
dc.date.issued2023-07
dc.description.abstractDiabetic Foot Ulcers (DFUs) are a devastating micro-vascular complication of diabetes with an increased prevalence and incidence and high rate of morbidity and mortality. Since antibiotics are frequently used to treat DFU, managing the condition has proven to be extremely challenging and may eventually lead to the development of antibiotic resistance. Scientists from around the world are working to develop an alternative solution to the problem of drug resistance by exploring complementary and alternative medicines that may be obtained from natural sources. Hence, the review aims to comprehensively report the information on the natural treatments and therapy used to manage DFU. All of the information described in the current study was gathered from electronic scientific resources, including Google Scholar, PubMed, Scopus, Science Direct, and Springer Link. Findings from the current review revealed the pre-clinical and clinical utility of 18 medicinal plants, 1 isolated compound, 7 polyherbal formulations including herbal creams, a few micronutrients including vitamins and minerals, insect products such as propolis, honey and, Maggot debridement therapy for the treatment and management of DFU. Natural therapies possess better efficacy, low cost, and shorter duration of treatment when compared with the conventional treatments; hence, all information made available about them is crucial to alter the di- rection of treatment. Furthermore, the data presented in this review are up to date on the potential efficacy of natural complementary medicines for alleviating DFU problems in in vitro and in vivo tests, as well as clinical studies.en_US
dc.identifier.affiliationsAssam Science and Technology University, Guwahati, 781013, Assam, India; Department of Pharmaceutical Chemistry, Girijananda Chowdhury Institute of Pharmaceutical Science, Girijananda Chowdhury University, Guwahati, 781017, Assam, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmaceutics, Girijananda Chowdhury Institute of Pharmaceutical Science, Girijananda Chowdhury University, Guwahati, 781017, Assam, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmacognosy, NETES Institute of Pharmaceutical Science, Mirza, 781101, Assam, Indiaen_US
dc.identifier.affiliationsAssam Science and Technology University, Guwahati, 781013, Assam, India; Department of Pharmaceutical Chemistry, Girijananda Chowdhury Institute of Pharmaceutical Science, Girijananda Chowdhury University, Guwahati, 781017, Assam, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmacognosy, NETES Institute of Pharmaceutical Science, Mirza, 781101, Assam, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmacology, Girijananda Chowdhury Institute of Pharmaceutical Science, Girijananda Chowdhury University, Guwahati, 781017, Assam, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmacognosy, R.T.M. Nagpur University, Nagpur, 440033, Indiaen_US
dc.identifier.affiliationsAssam Science and Technology University, Guwahati, 781013, Assam, India; Phytochemical Research Laboratory, Department of Pharmacognosy, Girijananda Chowdhury Institute of Pharmaceutical Science, Girijananda Chowdhury University, Guwahati, 781017, Assam, Indiaen_US
dc.identifier.citationKumar Suman, Bharali Alakesh, Sarma Himangshu, Kushari Susankar, Gam Sameeran, Hazarika Iswar, Prasad Satyendra K., Laloo Damiki . Traditional complementary and alternative medicine (TCAM) for diabetic foot ulcer management: A systematic review. Journal of Ayurveda and Integrative Medicine. 2023 Jul; 14(4): 1-11en_US
dc.identifier.issn0975-9476
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/236872
dc.languageenen_US
dc.publisherElsevier B.V.en_US
dc.relation.issuenumber4en_US
dc.relation.volume14en_US
dc.source.urihttps://doi.org/10.1016/j.jaim.2023.100745en_US
dc.subjectDiabetic foot ulceren_US
dc.subjectTraditional complementary and alternativeen_US
dc.subjectmedicineen_US
dc.subjectMedicinal plant extractsen_US
dc.subjectPolyherbal formulationen_US
dc.subjectClinical aspecten_US
dc.subjectMolecular mechanismen_US
dc.titleTraditional complementary and alternative medicine (TCAM) for diabetic foot ulcer management: A systematic reviewen_US
dc.typeJournal Articleen_US
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