Development of an interview-based warfarin nomogram predicting the time spent in the therapeutic INR range: A cost-effective, and non-invasive strategy building from a cross sectional study in a low resource setting

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dc.contributor.authorAnand, Aishwaryaen_US
dc.contributor.authorKumar, Rupeshen_US
dc.contributor.authorGupta, Ankuren_US
dc.contributor.authorVijayvergiya, Rajeshen_US
dc.contributor.authorMehrotra, Saurabhen_US
dc.contributor.authorLad, Deepeshen_US
dc.contributor.authorBarwad, Paragen_US
dc.contributor.authorSharma, Swatien_US
dc.contributor.authorPatil, Amol N.en_US
dc.date.accessioned2023-07-21T11:36:54Z
dc.date.available2023-07-21T11:36:54Z
dc.date.issued2022-06
dc.description.abstractA cross-sectional study was conducted to predict time in therapeutic range (TTR) using clinical history, examination, and socioeconomic data. Study included warfarin-receiving patients from outpatient-clinic. In 203 patients studied, mean warfarin start-dose was 2.55 mg/day and maintenance-dose/week was 30.79 mg. Body mass index (BMI) (p ¼ 0.03), warfarin maintenance dose/day (p ¼ 0.02), and comorbidity presence (p ¼ 0.04) were significantly associated with TTR. Occupation (p ¼ 0.53), income (p ¼ 0.83), education (p ¼ 0.55), and socioeconomic score (p ¼ 0.73) showed non-significant association with TTR. A TTR predicting nomogram was built from clinical history and examination findings.en_US
dc.identifier.affiliationsDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Indiaen_US
dc.identifier.affiliationsDepartment of Cardiothoracic and Vascular Surgery, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Indiaen_US
dc.identifier.affiliationsDepartment of Cardiology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Indiaen_US
dc.identifier.affiliationsDepartment of Internal Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Indiaen_US
dc.identifier.affiliationsDepartment of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Indiaen_US
dc.identifier.citationAnand Aishwarya, Kumar Rupesh, Gupta Ankur, Vijayvergiya Rajesh, Mehrotra Saurabh, Lad Deepesh, Barwad Parag, Sharma Swati, Patil Amol N.. Development of an interview-based warfarin nomogram predicting the time spent in the therapeutic INR range: A cost-effective, and non-invasive strategy building from a cross sectional study in a low resource setting. Indian Heart Journal. 2022 Jun; 74(3): 245-248en_US
dc.identifier.issn0019-4832
dc.identifier.issn2213-3763
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/220904
dc.languageenen_US
dc.publisherCardiological Society of Indiaen_US
dc.relation.issuenumber3en_US
dc.relation.volume74en_US
dc.source.urihttps://doi.org/10.1016/j.ihj.2022.03.008en_US
dc.subjectWarfarin nomogramen_US
dc.subjectPercent time in therapeutic rangeen_US
dc.subjectINRen_US
dc.titleDevelopment of an interview-based warfarin nomogram predicting the time spent in the therapeutic INR range: A cost-effective, and non-invasive strategy building from a cross sectional study in a low resource settingen_US
dc.typeJournal Articleen_US
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