Comparative efficacy of narrow-band ultraviolet B phototherapy alone and its combination with topical 8-methoxypsoralen in psoriasis.
| dc.contributor.author | Jain, V K | |
| dc.contributor.author | Jangra, Shobhna | |
| dc.contributor.author | Aggarwal, K | |
| dc.date.accessioned | 2012-08-27T05:21:30Z | |
| dc.date.available | 2012-08-27T05:21:30Z | |
| dc.date.issued | 2010-11 | |
| dc.description.abstract | Background: Very few studies using the combination of topical 8-methoxypsoralen (8-MOP) and narrow-band ultraviolet B (NBUVB) have been performed, especially in Indian patients. A combination of oral psoralen with NBUVB has been shown to have a superior efficacy as compared with NBUVB alone in psoriasis. Aims: Comparison of the efficacy of topical psoralen NBUVB (combination) versus NBUVB alone in psoriasis. Methods: Thirty patients with plaque psoriasis were taken up for the study and NBUVB phototherapy was given twice weekly. The target lesions on one side were treated with 0.1% topical 8-MOP 15 min before the irradiation. The treatment period was 12 weeks or 24 exposures. Results: The number of treatment sessions and cumulative NBUVB doses were lower in the combination therapy as compared with NBUVB monotherapy, although the differences were not statistically significant. Conclusion: To conclude, topical 8-MOP enhances the therapeutic effects of NBUVB therapy without increasing the incidence of adverse effects. | en_US |
| dc.identifier.citation | Jain V K, Jangra Shobhna, Aggarwal K. Comparative efficacy of narrow-band ultraviolet B phototherapy alone and its combination with topical 8-methoxypsoralen in psoriasis. Indian Journal of Dermatology, Venereology and Leprology. 2010 Nov-Dec; 76(6): 666-670. | en_US |
| dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/140726 | |
| dc.language.iso | en | en_US |
| dc.source.uri | https://www.ijdvl.com/article.asp?issn=0378-6323;year=2010;volume=76;issue=6;spage=666;epage=670;aulast=Jain | en_US |
| dc.subject | Narrow-band ultraviolet B phototherapy | en_US |
| dc.subject | topical 8-methoxypsoralen | en_US |
| dc.subject | psoriasis | en_US |
| dc.title | Comparative efficacy of narrow-band ultraviolet B phototherapy alone and its combination with topical 8-methoxypsoralen in psoriasis. | en_US |
| dc.type | Article | en_US |