A new recurring chromosome 13 abnormality in two older patients with de novo acute myeloid leukemia: An Indian experience.

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dc.contributor.authorTrivedi, P J
dc.contributor.authorPatel, P S
dc.contributor.authorBrahmbhatt, M M
dc.contributor.authorPatel, B P
dc.contributor.authorGajjar, S B
dc.contributor.authorDalal, E N
dc.contributor.authorShukla, S N
dc.contributor.authorShah, P M
dc.contributor.authorBakshi, S R
dc.date.accessioned2012-06-08T06:40:54Z
dc.date.available2012-06-08T06:40:54Z
dc.date.issued2009-09
dc.description.abstractWe report here two cases of trisomy 13 in acute myeloid leukemia M1 subtype. short-term unstimulated bone marrow and peripheral blood lymphocyte culture showed 47, XY, +13 in all metaphase plates and trisomy 13 was confirmed with whole chromosome paint probes. Trisomy 13 in AML-M1 is a rare numerical abnormality. This is the first Indian report of sole trisomy 13 in AML-M1. Here, we present two cases of elder male patients, which may constitute a distinct subtype.en_US
dc.identifier.citationTrivedi P J, Patel P S, Brahmbhatt M M, Patel B P, Gajjar S B, Dalal E N, Shukla S N, Shah P M, Bakshi S R. A new recurring chromosome 13 abnormality in two older patients with de novo acute myeloid leukemia: An Indian experience. Indian Journal of Human Genetics. 2009 Sept; 15(3): 137-139.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/138886
dc.language.isoenen_US
dc.source.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922630/en_US
dc.subjectAcute myeloid leukemia-M1en_US
dc.subjectrecurrenten_US
dc.subjectsole abnormalityen_US
dc.subjecttrisomy 13en_US
dc.subject.meshAged
dc.subject.meshBone Marrow Cells --cytology
dc.subject.meshCells, Cultures
dc.subject.meshChromosome Aberrations --genetics
dc.subject.meshChromosomes, Human, Pair 13 --genetics
dc.subject.meshHumans
dc.subject.meshLymphocytes --blood
dc.subject.meshLymphocytes --cytology
dc.subject.meshIndia --epidemiology
dc.subject.meshIn Situ Hybridization, Fluorescence --methods
dc.subject.meshLeukemia, Myeloid, Acute --diagnosis
dc.subject.meshLeukemia, Myeloid, Acute --genetics
dc.subject.meshMale
dc.subject.meshTrisomy --genetics
dc.titleA new recurring chromosome 13 abnormality in two older patients with de novo acute myeloid leukemia: An Indian experience.en_US
dc.typeArticleen_US
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