Response to purified chick embryo cell rabies vaccine administered intradermally for post-exposure prophylaxis.

dc.contributor.authorMadhusudana, S Nen_US
dc.contributor.authorAnand, N Pen_US
dc.date.accessioned1997-05-01en_US
dc.date.accessioned2009-06-03T06:03:01Z
dc.date.available1997-05-01en_US
dc.date.available2009-06-03T06:03:01Z
dc.date.issued1997-05-01en_US
dc.description.abstractBACKGROUND: Post-exposure immunization of rabies with presently available cell culture vaccines in the regular five-dose intramuscular schedule is expensive for developing countries. In view of the latest World Health Organization recommendation on the use of the abbreviated intradermal regimen (now routinely followed in Thailand), we evaluated this regimen for the purified chick embryo cell vaccine. METHODS: Twenty-five subjects who had nursed or casually handled a rabies patient were administered purified chick embryo cell vaccine. RESULTS: There was 100% seroconversion and all the subjects developed neutralizing antibody levels higher than the adequate level of 0.5 i.u./ml. Only minor side-effects were observed in some subjects. CONCLUSION: The feasibility of using this regimen in routine practice needs to be evaluated further.en_US
dc.description.affiliationDepartment of Neurovirology, Ramiah Medical College, Bangalore, Karnataka, India.en_US
dc.identifier.citationMadhusudana SN, Anand NP. Response to purified chick embryo cell rabies vaccine administered intradermally for post-exposure prophylaxis. National Medical Journal of India. 1997 May-Jun; 10(3): 115-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/118784
dc.language.isoengen_US
dc.source.urihttps://www.nmji.inen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAllied Health Personnelen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntibodies, Viral --analysisen_US
dc.subject.meshChick Embryoen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInjections, Intradermalen_US
dc.subject.meshMaleen_US
dc.subject.meshOccupational Exposure --prevention & controlen_US
dc.subject.meshRabies --prevention & controlen_US
dc.subject.meshRabies Vaccines --administration & dosageen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleResponse to purified chick embryo cell rabies vaccine administered intradermally for post-exposure prophylaxis.en_US
dc.typeJournal Articleen_US
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