Bacterial meningitis in children: etiology and clinical features, an 11-year review of 618 cases.

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dc.contributor.authorChotpitayasunondh, Ten_US
dc.date.accessioned2009-05-27T14:56:03Z
dc.date.available2009-05-27T14:56:03Z
dc.date.issued1994-03-01en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractDuring the period January 1980 to December 1990 (11 years) a retrospective study of patients with bacterial meningitis who were admitted to Bangkok Children's Hospital was carried out. There were 618 patients with 77 cases (12.5%) occurring below the age of one month (neonatal meningitis), and 541 cases (87.5%) between one month to 15 years (childhood meningitis). Pseudomonas aeruginosa was the most common pathogenic organism (16.9%) in neonatal meningitis; other causative agents in this age group included Klebsiella pneumoniae (13.0%), group B Streptococcus (11.7%), Escherichia coli and Enterobacter sp (10.4% each). In childhood meningitis, Haemophilus influenzae was the most common causative organism (42.3%), and followed by Streptococcus pneumoniae (22.2%) and Salmonella sp (12.4%). Excluding a 13 year-old leukemic patient, Salmonella meningitis occurred exclusively in infants, 87% of them were under six months, and 13% of them developed relapsing meningitis. Presenting symptoms and signs on admission of neonatal meningitis such as fever (81.8%), convulsions (45.4%), neck stiffness (22.5%), bulging fontanelle (33.3%) and Brudzinski sign (11.5%) were significantly less frequent than in the patients beyond the neonatal period (p < 0.05). The overall fatalities during 1980-1990 were 45.4% and 17.3% for neonatal meningitis and childhood meningitis, respectively. The fatalities of the two age groups declined significantly during 1987-1990 to 26.3% and 11.4% respectively.en_US
dc.description.affiliationChildren's Hospital, Ministry of Public Health, Bangkok, Thailand.en_US
dc.identifier.citationChotpitayasunondh T. Bacterial meningitis in children: etiology and clinical features, an 11-year review of 618 cases. The Southeast Asian Journal of Tropical Medicine and Public Health. 1994 Mar; 25(1): 107-15en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/31475
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/publication.htmen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAge Factorsen_US
dc.subject.meshCause of Deathen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIncidenceen_US
dc.subject.meshInfanten_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshMaleen_US
dc.subject.meshMeningitis, Bacterial --cerebrospinal fluiden_US
dc.subject.meshPopulation Surveillanceen_US
dc.subject.meshPrognosisen_US
dc.subject.meshRecurrenceen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshThailand --epidemiologyen_US
dc.titleBacterial meningitis in children: etiology and clinical features, an 11-year review of 618 cases.en_US
dc.typeJournal Articleen_US
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