Hemophagocytic Lymphohistiocytosis (HLH) Associated With Scrub Typhus: Report Of 2 Cases

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dc.contributor.authorGomber, Apoorvaen_US
dc.contributor.authorKumar, Vijayen_US
dc.contributor.authorSingh, Shashikanten_US
dc.contributor.authorKishore, Manjarien_US
dc.contributor.authorMarwah, Sadhnaen_US
dc.date.accessioned2020-01-02T06:31:26Z
dc.date.available2020-01-02T06:31:26Z
dc.date.issued2019-11
dc.description.abstractHemophagocytic Lymphohistiocytosis (HLH) is a fatal hyperinflammatory syndrome characterized by histiocytic proliferation along with hemophagocytosis. HLH can be primary (inherited) or secondary, to any severe infection, malignancy or rheumatological disease. HLH, though rare, has also been noted in association with scrub typhus which is an acute febrile illness resulting from the bite of infected larval form of mite (also known as chigger). We hereby describe two cases of HLH associated with rickettsial infection (Oriental tsutsugamushi) in a 36-year-old male and in a 10-year-old male child. The former presented with high-grade fever and pruritic macular rash over abdomen. While the latter was presented with fever and decreased urinary output at the time of admissionen_US
dc.identifier.affiliationsPostgraduate, Department of Pathology, PGIMER, Dr. Ram Manohar Lohia Hospital, Delhi, New Delhi, Indiaen_US
dc.identifier.affiliationsProfessor, Department of Pathology, PGIMER, Dr. Ram Manohar Lohia Hospital, Delhi, New Delhi, Indiaen_US
dc.identifier.affiliationsPostgraduate Student, Department of Pathology, PGIMER, Dr. Ram Manohar Lohia Hospital, Delhi, New Delhi, Indiaen_US
dc.identifier.affiliationsSenior Resident, Department of Pathology, PGIMER, Dr. Ram Manohar Lohia Hospital, Delhi, New Delhi, Indiaen_US
dc.identifier.citationGomber Apoorva, Kumar Vijay, Singh Shashikant, Kishore Manjari, Marwah Sadhna. Hemophagocytic Lymphohistiocytosis (HLH) Associated With Scrub Typhus: Report Of 2 Cases. Indian Journal of Case Reports. 2019 Nov; 5(6): 1-4en_US
dc.identifier.issn2454-129X
dc.identifier.issn2454-1303
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/190806
dc.languageenen_US
dc.publisherAtharva Scientific Publicationsen_US
dc.relation.issuenumber6en_US
dc.relation.volume5en_US
dc.source.urihttps://atharvapub.net/IJCR/article/view/1940/1541en_US
dc.titleHemophagocytic Lymphohistiocytosis (HLH) Associated With Scrub Typhus: Report Of 2 Casesen_US
dc.typeJournal Articleen_US
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