Use of 99mTc-sulfur colloid to assess lymphatic dysfunction in filarial infection.

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dc.contributor.authorJenkins, V Ken_US
dc.contributor.authorEwert, Aen_US
dc.contributor.authorJohnson, R Fen_US
dc.contributor.authorFolse, D Sen_US
dc.date.accessioned2009-05-27T14:35:58Z
dc.date.available2009-05-27T14:35:58Z
dc.date.issued1985-09-01en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractInvestigations of lymphatic dysfunction in animals infected with filarial parasites has been hampered by a paucity of techniques to measure efficiency of lymphatic drainage. In this study a 99mTc-sulfur colloid technique was used to assess the efficiency of lymphatic drainage in Patas monkeys infected with filarial nematodes. In all 15 uninfected hind limbs there was rapid and consistent appearance of labeled colloid in the primary lymph node (popliteal) and subsequently in the secondary nodes (abdomino-pelvic) in 11 of 15 limbs. In contrast, in all eight limbs tested 1-9 months after infection there was reduced rate of migration of the colloid and initial appearance in the abdomino-pelvic region: subsequent accumulation was seen in the popliteal region in only four of the limbs. This data indicated that lymphatic vessels were blocked and that collateral vessels channeled the colloid to the secondary lymph nodes. The lymph flow patterns demonstrated by the isotope technique were supported at autopsy.en_US
dc.identifier.citationJenkins VK, Ewert A, Johnson RF, Folse DS. Use of 99mTc-sulfur colloid to assess lymphatic dysfunction in filarial infection. The Southeast Asian Journal of Tropical Medicine and Public Health. 1985 Sep; 16(3): 387-94en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/30565
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/publication.htmen_US
dc.subject.meshAnimalsen_US
dc.subject.meshErythrocebus patasen_US
dc.subject.meshExtremitiesen_US
dc.subject.meshFemaleen_US
dc.subject.meshFilariasis --pathologyen_US
dc.subject.meshLymphatic System --pathologyen_US
dc.subject.meshMaleen_US
dc.subject.meshTechnetium Tc 99m Sulfur Colloid --diagnostic useen_US
dc.titleUse of 99mTc-sulfur colloid to assess lymphatic dysfunction in filarial infection.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, U.S. Gov't, P.H.S.en_US
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