Dental plaque: an unlikely reservoir of Helicobacter pylori.

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dc.contributor.authorKamat, A Hen_US
dc.contributor.authorMehta, P Ren_US
dc.contributor.authorNatu, A Aen_US
dc.contributor.authorPhadke, A Yen_US
dc.contributor.authorVora, I Men_US
dc.contributor.authorDesai, P Den_US
dc.contributor.authorKoppikar, G Ven_US
dc.date.accessioned1998-10-31en_US
dc.date.accessioned2009-05-29T03:23:32Z
dc.date.available1998-10-31en_US
dc.date.available2009-05-29T03:23:32Z
dc.date.issued1998-10-31en_US
dc.description.abstractBACKGROUND AND AIM: Dental plaque has been suggested as a reservoir for Helicobacter pylori, though data in this regard are conflicting. We evaluated the prevalence of H. pylori DNA in dental plaque using polymerase chain reaction (PCR). METHODS: Antral H. pylori status of 156 patients with acid-peptic disease (APD) was studied by rapid urease test (RUT), histology and culture. Dental plaque obtained from these 156 patients and 92 healthy volunteers was evaluated for the presence of H. pylori using RUT, culture and PCR. RESULTS: H. pylori was present in 133 antral biopsy samples by RUT and/or histology. The dental plaque of 37 patients with APD and 21 healthy volunteers tested positive by RUT. H. pylori was not isolated by culture from any of the dental plaques. PCR gave a significant amplification product in 11 of 248 (4.4%) dental plaque samples, 7 from patients with APD and 4 from normal healthy volunteers. CONCLUSION: The frequency of H. pylori in the dental plaque is low, and this is unlikely to be a prominent site of infection with H. pylori.en_US
dc.description.affiliationDepartment of Microbiology, B Y L Nair Ch Hospital, Mumbai.en_US
dc.identifier.citationKamat AH, Mehta PR, Natu AA, Phadke AY, Vora IM, Desai PD, Koppikar GV. Dental plaque: an unlikely reservoir of Helicobacter pylori. Indian Journal of Gastroenterology. 1998 Oct-Dec; 17(4): 138-40en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/65281
dc.language.isoengen_US
dc.source.urihttps://www.indianjgastro.comen_US
dc.subject.meshAdulten_US
dc.subject.meshCase-Control Studiesen_US
dc.subject.meshDNA Primersen_US
dc.subject.meshDental Plaque --microbiologyen_US
dc.subject.meshDisease Reservoirsen_US
dc.subject.meshDyspepsia --microbiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHelicobacter Infections --microbiologyen_US
dc.subject.meshHelicobacter pylori --isolation & purificationen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPolymerase Chain Reactionen_US
dc.subject.meshPrevalenceen_US
dc.titleDental plaque: an unlikely reservoir of Helicobacter pylori.en_US
dc.typeJournal Articleen_US
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