Mortality audit of COVID-19 infection among children

Simple item page
dc.contributor.authorSharma, Ramanen_US
dc.contributor.authorAgarwal, Ashishen_US
dc.contributor.authorRanjan, Ankiten_US
dc.contributor.authorJayashree, Muralidharanen_US
dc.contributor.authorKumar, Praveenen_US
dc.date.accessioned2023-08-19T04:52:11Z
dc.date.available2023-08-19T04:52:11Z
dc.date.issued2022-06
dc.description.abstractBackground & objectives: As severe COVID-19 and mortality are not common in children, there is a scarcity of data regarding the cause of mortality in children infected with SARS-CoV-2. This study was aimed to describe the all-cause mortality and COVID-19 death (disease-specific mortality) in children with SARS-CoV-2 infection admitted to a paediatric COVID facility in a tertiary care centre. Methods: Data with respect to clinical, epidemiological profile and causes of death in non-survivors (0-12 yr old) of SARS-CoV-2 infection admitted to a dedicated tertiary care COVID hospital in north India between April 2020 and June 2021 were retrieved and analyzed retrospectively. Results: A total of 475 SARS-CoV-2–positive children were admitted during the study period, of whom 47 died [18 neonates, 14 post-neonatal infants and 15 children (1-12 yr of age)]. The all-cause mortality and COVID-19 death (disease-specific mortality) were 9.9 per cent (47 of 475) and 1.9 per cent (9 of 475), respectively. Underlying comorbidities were present in 35 (74.5%) children, the most common being prematurity and perinatal complications (n=11, 24%) followed by congenital heart disease (n=6, 13%). The common causes of death included septic shock in 10 (21%), COVID pneumonia/severe acute respiratory distress syndrome in nine (19%), neonatal illnesses in eight (17%), primary central nervous system disease in seven (15%) and congenital heart disease with complication in six (13%) children. Interpretation & conclusions: Our results showed a high prevalence of underlying comorbidities and a low COVID-19 death (disease-specific mortality). Our findings highlight that mortality due to COVID-19 can be overestimated if COVID-19 death and all-cause mortality in children infected with SARS-CoV-2 are not separated. Standardized recording of cause of death in children with SARS-CoV-2 infection is important.en_US
dc.identifier.affiliationsDivision of Paediatric Emergency & Critical Care &en_US
dc.identifier.affiliationsDivision of Neonatology, Department of Paediatrics, Advanced Paediatrics Centre, Postgraduate Institute of Medical Education & Research, Chandigarh, Indiaen_US
dc.identifier.citationSharma Raman, Agarwal Ashish, Ranjan Ankit, Jayashree Muralidharan , Kumar Praveen. Mortality audit of COVID-19 infection among children. Indian Journal of Medical Research. 2022 Jun; 155(5-6): 505–509en_US
dc.identifier.issn0971-5916
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/223621
dc.languageenen_US
dc.publisherWolters Kluwer – Medknowen_US
dc.relation.issuenumber5-6en_US
dc.relation.volume155en_US
dc.source.urihttps://doi.org/10.4103/ijmr.ijmr_2500_21en_US
dc.subjectAuditen_US
dc.subjectcomorbiditiesen_US
dc.subjectCOVID-19en_US
dc.subjectmortalityen_US
dc.subjectpaediatricen_US
dc.subjectSARS-CoV-2en_US
dc.titleMortality audit of COVID-19 infection among childrenen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
IJMR2022v155n5-6p505.pdf
Size:
609.88 KB
Format:
Adobe Portable Document Format
Download
Collections
Indian Journal of Medical Research