Study of maternal serum lipid profile and apolipoprotein a levels and its correlation with fetal growth restriction

Simple item page
dc.contributor.authorDevi, Akoijam Tamphasanaen_US
dc.contributor.authorYadav, Reenaen_US
dc.contributor.authorYadav, Amitaen_US
dc.contributor.authorSingh, Yanglem Ajitkumaren_US
dc.date.accessioned2020-10-16T08:01:39Z
dc.date.available2020-10-16T08:01:39Z
dc.date.issued2020-01
dc.description.abstractBackground: This study was aimed to estimate maternal serum lipid profile and apolipoprotein A levels in pregnancies complicated with FGR and to compare the levels with the levels in normal pregnancies.Methods: A prospective observational study was conducted in Lady Hardinge Medical College, New Delhi, in a study group consisting of 30 pregnant women at gestation 32-34 weeks with ultrasound diagnosed FGR and control group consisting of 30 age and gestation matched uncomplicated pregnant women. Maternal serum lipid profile and apolipoprotein A levels were measured and compared between the two groups.Results: Total serum cholesterol, triglyceride, LDL-cholesterol, VLDL-cholesterol and Apolipoprotein A were significantly lower in FGR group compared to normal controls. Mean±SD of total cholesterol was found to be 199.17±49.06 mg/dl in cases and 244.10±53.17 mg/dl in controls. Mean±SD of triglyceride was 200.53±60.25 mg/dl in cases compared to 304.13±69.12 mg/dl in controls. Mean±SD of LDL-Cholesterol was 98.19±37.91 mg/dl in cases and 127.07±47.84 mg/dl in controls. Mean±SD of VLDL-cholesterol was 40.11±12.05 mg/dl in cases and 60.83±13.82 mg/dl in controls. Mean±SD of Apolipoprotein A was 147.71±16.40 mg/dl in cases compared to 163.30±16.07 mg/dl in controls. HDL-cholesterol did not change significantly as its mean±SD was 60.87±15.18 mg/dl in FGR group and 56.20±16.07 mg/dl in control group.Conclusions: The decreased levels of total cholesterol, triglyceride, LDL-cholesterol, VLDL-cholesterol and apolipoprotein A levels may be used as biochemical marker for detection of FGR.en_US
dc.identifier.affiliationsDepartment of Obstetrics and Gynecology, Regional Institute of Medical Sciences, Imphal, Manipur, Indiaen_US
dc.identifier.affiliationsDepartment of Obstetrics and Gynecology, Lady Hardinge Medical College, New Delhi, Indiaen_US
dc.identifier.affiliationsDepartment of Biochemistry, Vardhaman Mahavir Medical College and Safdarjung Hospital, New Delhi, Indiaen_US
dc.identifier.citationDevi Akoijam Tamphasana, Yadav Reena, Yadav Amita, Singh Yanglem Ajitkumar. Study of maternal serum lipid profile and apolipoprotein a levels and its correlation with fetal growth restriction. International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2020 Jan; 9(1): 270-273en_US
dc.identifier.issn2320-1770
dc.identifier.issn2320-1789
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/207346
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber1en_US
dc.relation.volume9en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-1770.ijrcog20196032en_US
dc.subjectApolipoprotein Aen_US
dc.subjectCholesterolen_US
dc.subjectFetal growth restrictionen_US
dc.subjectTriglycerideen_US
dc.titleStudy of maternal serum lipid profile and apolipoprotein a levels and its correlation with fetal growth restrictionen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijrcog2020v9n1p270.pdf
Size:
90.32 KB
Format:
Adobe Portable Document Format
Download
Collections
International Journal of Reproduction, Contraception, Obstetrics and Gynecology