Psammomatous melanotic schwannoma as a component of Carney complex.
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Date
2015-07
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Abstract
Melanotic schwannoma is a rare form of pigmented neural tumor commonly
arising from the posterior spinal nerves and ganglia. Two variants have been
described, psammomatous and nonpsammomatous. 50% of psammomatous
tumors are associated with Carney complex. The biologic behavior of the tumor
is diffi cult to predict and slightly over 10% of the tumors follow malignant course.
We present a case of psammomatous melanotic schwannoma as part of Carney
complex in a 67-year-old male. Clinical examination revealed oral mucosal
and abdominal skin pigmentation. Magnetic resonance imaging showed an
intradural extramedullary lesion at D8-D12 level. Intraoperative squash smear
study showed sheets of spindle cells with abundant intracytoplasmic melanin
pigmentation and few psammoma bodies. Based on clinical, radiologic, and
histopathological fi ndings with immunohistochemistry correlation a fi nal diagnosis
of psammomatous melanotic schwannoma was rendered.
Description
Keywords
Carney complex, melanotic schwannoma, psammoma bodies
Citation
Shanmugam Salapathi, Ghosh Mitra, Niamathullah Sadiya, Ghosh Siddhartha. Psammomatous melanotic schwannoma as a component of Carney complex. Indian Journal of Pathology & Microbiology. 2015 Jul-Sept 58(3): 368-370.