alpha 1-Antitrypsin deficiency in Indian patients with chronic obstructive airways and other pulmonary diseases.

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dc.contributor.authorRay, Den_US
dc.contributor.authorKanagasabapathy, A Sen_US
dc.contributor.authorJairaj, P Sen_US
dc.date.accessioned2009-05-28T05:27:41Z
dc.date.available2009-05-28T05:27:41Z
dc.date.issued1994-06-01en_US
dc.descriptionThe Ceylon Medical Journal.en_US
dc.description.abstractOBJECTIVE: To determine alpha 1-antitrypsin (A1AT) deficiency in patients with chronic obstructive airways disease (COAD) and other pulmonary diseases. DESIGN: Observation study. SUBJECTS: 45 patients with COAD, 20 with bronchiectasis, 11 with pulmonary tuberculosis, 25 with chest malignancies and 42 healthy subjects. SETTING: Christian Medical College Hospital, Vellore, India. MAIN OUTCOME MEASURE: Serum A1AT level of 10% or less of the mean serum value of the control group was recognised as severe deficiency and A1AT level between 10 and 60% was considered as intermediate deficiency. RESULTS: 26 patients (18 with COAD, 2 with bronchiectasis, 3 with tuberculosis and 3 with chest malignancies) had intermediate A1AT deficiency. CONCLUSION: The finding of an A1AT deficiency in over a quarter of the patients comprising various categories of pulmonary diseases emphasises the need to explore the possibility of an underlying acquired cause existing either alone or in association with genetic defect in patients showing such a deficiency.en_US
dc.description.affiliationDepartment of Chest Diseases, Christian Medical College, Vellore, India.en_US
dc.identifier.citationRay D, Kanagasabapathy AS, Jairaj PS. alpha 1-Antitrypsin deficiency in Indian patients with chronic obstructive airways and other pulmonary diseases. The Ceylon Medical Journal. 1994 Jun; 39(2): 77-81en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/48513
dc.language.isoengen_US
dc.source.urihttps://www.infolanka.com/CMJhome/en_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAge Factorsen_US
dc.subject.meshAgeden_US
dc.subject.meshBiological Markers --blooden_US
dc.subject.meshBronchiectasis --blooden_US
dc.subject.meshChilden_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIndiaen_US
dc.subject.meshLung Diseases, Obstructive --blooden_US
dc.subject.meshLung Neoplasms --blooden_US
dc.subject.meshLung Volume Measurementsen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPilot Projectsen_US
dc.subject.meshSex Factorsen_US
dc.subject.meshTuberculosis, Pulmonary --blooden_US
dc.subject.meshTumor Markers, Biological --blooden_US
dc.subject.meshalpha 1-Antitrypsin Deficiencyen_US
dc.titlealpha 1-Antitrypsin deficiency in Indian patients with chronic obstructive airways and other pulmonary diseases.en_US
dc.typeJournal Articleen_US
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