Mycosis fungoides and Sezary syndrome – Simplifying the approach for dermatologists. Part 2: Evaluation, staging, prognosis and treatment
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Date
2025-04
Journal Title
Journal ISSN
Volume Title
Publisher
Scientific Scholar on behalf of Indian Association of Dermatologists, Venereologists & Leprologists (IADVL), India.
Abstract
Cutaneous T-cell lymphoma is a heterogeneous group of T-cell neoplasms, of which mycosis fungoides and Sezary syndrome are the most common. The prognosis depends on the stage of the disease. The early stage follows a protracted course with a five-year disease-specific survival of greater than 95% and is treated with skin-directed topical therapies, phototherapy, and oral drugs like methotrexate. Advanced disease has a five-year overall survival of less than 25% and requires management by systemic chemotherapeutic agents. This review article is the second part out of the two covering the staging, prognosis, and treatment from a dermatologist’s perspective.
Description
Keywords
Mycosis fungoides, Sezary syndrome, CTCL, cutaneous T cell lymphoma
Citation
Singh GK, Das P, Srivastava S, Singh K, Singh V, Barui S, Mulajkar D, Dubey IP.. Mycosis fungoides and Sezary syndrome – Simplifying the approach for dermatologists. Part 2: Evaluation, staging, prognosis and treatment. Indian Journal of Dermatology, Venereology and Leprology. 2025 Apr; 91(2): 180-187