Expression of CD71 by flow cytometry in acute leukemias: More often seen in acute myeloid leukemia.

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dc.contributor.authorPande, Amit
dc.contributor.authorDorwal, Pranav
dc.contributor.authorJain, Dharmendra
dc.contributor.authorTyagi, Neetu
dc.contributor.authorMehra, Simmi
dc.contributor.authorSachdev, Ritesh
dc.contributor.authorRaina, Vimarsh
dc.date.accessioned2016-12-08T07:33:11Z
dc.date.available2016-12-08T07:33:11Z
dc.date.issued2016-07
dc.description.abstractBackground: CD71 is a marker that has been usually used for identifying dysplasia in the erythroid series. We have tried to evaluate the expression of CD71 in various types of acute leukemias. Materials and Methods: We studied 48 patients of acute leukemia, of which 25 were acute myeloid leukemia (AML), 13 were precursor B‑acute lymphoblastic leukemia (B‑ALL), 8 were T‑ALL, and 2 were mixed phenotype acute leukemia (T/myeloid) as per the WHO classification. Results: We found that the expression of CD71 was most prevalent in AMLs (84%), followed by T‑ALL (50%) and least in B‑ALL (30%). Conclusion: This finding clearly shows the higher expression of CD71 in AMLs compared to other common type of leukemias, such as B‑ and T‑ALL. We suggest that the high expression of CD71 in AMLs could be used as a diagnostic marker and may also be used for minimal residual disease analysis after further studies in posttreatment scenario. This study is the first of its kind in the South Asian population.en_US
dc.identifier.citationPande Amit, Dorwal Pranav, Jain Dharmendra, Tyagi Neetu, Mehra Simmi, Sachdev Ritesh, Raina Vimarsh. Expression of CD71 by flow cytometry in acute leukemias: More often seen in acute myeloid leukemia. Indian Journal of Pathology & Microbiology. 2016 July-Sept 59(3): 310-313.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/179557
dc.language.isoenen_US
dc.source.urihttps://www.ijpmonline.org/article.asp?issn=0377-4929;year=2016;volume=59;issue=3;spage=310;epage=313;aulast=Pandeen_US
dc.subjectAcute leukemiaen_US
dc.subjectacute lymphoblastic leukemiaen_US
dc.subjectacute myeloid leukemiaen_US
dc.subjectCD71en_US
dc.subjectflow cytometryen_US
dc.titleExpression of CD71 by flow cytometry in acute leukemias: More often seen in acute myeloid leukemia.en_US
dc.typeArticleen_US
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