Primary cutaneous B-cell lymphoma: A single-center 5-year experience
dc.contributor.author | Jacob, Linu Abraham | en_US |
dc.contributor.author | Asati, Vikas | en_US |
dc.contributor.author | Lakshmaiah, KC | en_US |
dc.contributor.author | Babu, K Govind | en_US |
dc.contributor.author | Lokanatha, Dasappa | en_US |
dc.contributor.author | Babu, Suresh MC | en_US |
dc.contributor.author | KN, Lokesh | en_US |
dc.contributor.author | AH, Rudresh | en_US |
dc.contributor.author | LK, Rajeev | en_US |
dc.contributor.author | Nikita J Mulchandani | en_US |
dc.contributor.author | Anand, Abhishek | en_US |
dc.contributor.author | Koppaka, Deepak | en_US |
dc.contributor.author | Mysore, Suma Narayana | en_US |
dc.date.accessioned | 2020-01-02T06:27:59Z | |
dc.date.available | 2020-01-02T06:27:59Z | |
dc.date.issued | 2018-04 | |
dc.description.abstract | BACKGROUND: Skin is the second most common site for extranodal non-Hodgkin's lymphoma (NHL). Most primary cutaneous NHLs are of T-cell origin (70%). Primary cutaneous B-cell lymphoma (PCBCL) is a rare entity. MATERIALS AND METHODS: Patients diagnosed with PCBCL between January 2012 and July 2017 at our center were retrospectively analyzed. RESULTS: Eight patients of PCBCL were diagnosed. Three patients (37.5%) were males while 5 patients (62.5%) were females. The median age at diagnosis was 45 years (range, 18–60 years). Scalp was the most common site of involvement (50% of the patients). Diffuse large B-cell lymphoma (DLBCL) was the most common histology (63%), with leg-type DLBCL diagnosed in 1 patient. Two patients had primary cutaneous follicle center lymphoma, whereas the remaining 1 patient had precursor B-lymphoblastic lymphoma. All 5 DLBCL cases were treated with CHOP chemotherapy, and rituximab was given to 3 patients. Of the primary cutaneous follicle center lymphomas, 1 patient with stage II disease was treated with CHOP and is alive without recurrence for the past 5 years, whereas the other patient is on observation alone. The patient with precursor B-lymphoblastic lymphoma was started on MCP-841 protocol; however, the patient did not complete the treatment and died after 11 months. CONCLUSIONS: PCBCL is a heterogeneous group of diseases and dividing them into subtypes, based on morphology and immunophenotype, has therapeutic implications. | en_US |
dc.identifier.affiliations | Department of Medical Oncology, Kidwai Cancer Institute, Bengaluru, Karnataka, India | en_US |
dc.identifier.citation | Jacob Linu Abraham, Asati Vikas, Lakshmaiah KC, Babu K Govind, Lokanatha Dasappa, Babu Suresh MC, KN Lokesh, AH Rudresh, LK Rajeev, Nikita J Mulchandani, Anand Abhishek, Koppaka Deepak, Mysore Suma Narayana. Primary cutaneous B-cell lymphoma: A single-center 5-year experience. Indian Journal of Cancer. 2018 Apr; 55(2): 134-136 | en_US |
dc.identifier.issn | 0019-509X | |
dc.identifier.place | India | en_US |
dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/190334 | |
dc.language | en | en_US |
dc.publisher | Indian Cancer Society | en_US |
dc.relation.issuenumber | 2 | en_US |
dc.relation.volume | 55 | en_US |
dc.source.uri | https://dx.doi.org//10.4103/ijc.IJC_418_17 | en_US |
dc.title | Primary cutaneous B-cell lymphoma: A single-center 5-year experience | en_US |
dc.type | Journal Article | en_US |
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