Low blood glutathione levels in acute myocardial infarction.

Simple item page
dc.contributor.authorKharb, Simmien_US
dc.date.accessioned2003-08-29en_US
dc.date.accessioned2009-05-29T06:47:39Z
dc.date.available2003-08-29en_US
dc.date.available2009-05-29T06:47:39Z
dc.date.issued2003-08-29en_US
dc.description.abstractBACKGROUND: Although experimental studies have demonstrated that reduced glutathione (GSH) is involved in cellular protection from deleterious effects of oxygen free radicals in ischaemia and reperfusion, there are controversial data on the correlation between levels of GSH and the ischaemic process. AIM: The present study was planned to evaluate erythrocyte GSH levels in patients with acute myocardial infarction (AMI). SETTING & DESIGN: Erythrocyte GSH levels were determined in 22 patients with AMI and 15 age matched healthy volunteers served as control. MATERIAL & METHODS: Erythrocyte GSH levels were measured by using Bentler in AMI and control patients. Also lipid profile was analyzed enzymatically in these subject. STATISTICS: The values were expressed as means +/- standard deviation (SD) and data from patients and controls was compared using student's 't'-test. Results and CONCLUSION: GSH levels were significantly decreased in AMI as compared to control (p<0.001). Also, total cholesterol and triglycerides were higher is AMI subjects (p<0.05). These finding suggest that depressed GSH levels may be associated with enhanced protective mechanism to oxidative stress in AMI.en_US
dc.description.affiliationDepartment of Biochemistry, Pt. B.D. Sharma PGIMS, Rohtak, Haryana. simmikh@rediffmail.comen_US
dc.identifier.citationKharb S. Low blood glutathione levels in acute myocardial infarction. Indian Journal of Medical Sciences. 2003 Aug; 57(8): 335-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/69215
dc.language.isoengen_US
dc.source.urihttps://www.indianjmedsci.orgen_US
dc.subject.meshBiological Markersen_US
dc.subject.meshCholesterol --blooden_US
dc.subject.meshGlutathione --blooden_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMalondialdehyde --blooden_US
dc.subject.meshMyocardial Infarction --blooden_US
dc.subject.meshReference Valuesen_US
dc.subject.meshTriglycerides --blooden_US
dc.titleLow blood glutathione levels in acute myocardial infarction.en_US
dc.typeClinical Trialen_US
dc.typeControlled Clinical Trialen_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Journal of Medical Sciences