Opportunistic Strongyloides Stercoralis Infection in an Immunocompromised Patient.
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Date
2012-12
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Abstract
Strongyloides stercoralis is an intestinal nematode that
infects human percutaneously and has a complex life cycle
including a direct, an autoinfective and a non-parasitic freeliving
developmental cycle. Strongyloidiasis has a worldwide
distribution, and usually causes mild or asymptomatic
infection. However hyperinfection syndrome can cause
significant morbidity and mortality in immunocompromised
states such as malignancy, HIV infection, or
immunosuppressive agent administration. We report a case
of a 37-year old male HIV positive patient admitted in male
medical ward, RIMS with severe diarrhoea, pain abdomen,
generalized weakness and history of diarrhoea off and on
for past one month. His CD4+ T- lymphocyte count was
116 cell/microlitre and the patient was on antiretroviral
therapy. Stool examination reveals larvae of Strongyloides
stercoralis. Stool culture was negative for pathogenic bacteria
and fungi. Special staining for detection of intestinal coccidian
parasites and microsporidiosis was also negative .The patient
was successfully treated with combined therapy of
albendazole(400mg) and ivermectin(6mg) daily for 3days.
Description
Keywords
HIV, Strongyloides stercoralis, Manipur
Citation
Sarkar Abhijit, Devi Pukhrambam Pratita, Singh H. Rebachandra, Singh Ng Brajachand. Opportunistic Strongyloides Stercoralis Infection in an Immunocompromised Patient. Indian Medical Gazette. 2012 Dec ; 145 (12): 497-500.