Effect of Raised Mid-trimester Serum hCG and a-fetoprotein on Pregnancy Outcome.
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Date
2013-03
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Abstract
Objective: To study the effect of elevated maternal serum human choriogonadotrophin (MShCG) levels and maternal serum
a-fetoprotein (MSAFP) levels measured at 14-24 weeks gestation on pregnancy outcome. Material and methods: A prospective
study was conducted in 400 antenatal women with gestational age 14-24 weeks attending OPD and Indoor in Dept. of Obstetrics
and Gynecology over a period of 12 months. Maternal serum b-hCG and a-fetoprotein levels were measured by fully automated
chemiluminesence method. Result: Elevated mid-trimester MShCG levels and MSAFP level were associated with development
of pre-eclampsia. Conclusion: Elevated mid-trimester MShCG and MSAFP level may help in the prediction of pre-eclampsia
and hence they can be used as screening tools for prediction of pre-eclampsia.
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Keywords
Human choriogonadotrophin, maternal serum a-fetoprotein, pre-eclampsia
Citation
Dubey Preeti, Pandey Kiran, Agarwal Shaily, Jain Sunita, Singh Neetu, Gupta Shilpi. Effect of Raised Mid-trimester Serum hCG and a-fetoprotein on Pregnancy Outcome. Indian Journal of Clinical Practice. 2013 Mar; 23(10): 645-647.