An Apgar score of three or less at one minute is not diagnostic of birth asphyxia but is a useful screening test for neonatal encephalopathy.

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dc.contributor.authorEllis, Men_US
dc.contributor.authorManandhar, Nen_US
dc.contributor.authorManandhar, D Sen_US
dc.contributor.authordeL Costello, A Men_US
dc.date.accessioned1998-05-27en_US
dc.date.accessioned2009-05-27T05:16:23Z
dc.date.available1998-05-27en_US
dc.date.available2009-05-27T05:16:23Z
dc.date.issued1998-05-27en_US
dc.description.abstractOBJECTIVE: To evaluate the relationship between an Apgar score of three or less at one minute of life and the subsequent risk of developing neonatal encephalopathy (NE). DESIGN: Prospective. SETTING: The principal maternity hospital of Kathmandu, Nepal, a low income country, where over 50% of the local population deliver. METHODS: All liveborn infants over a 12 month period with a birthweight of 500 g or more were assessed by the Apgar scoring system at one minute of age. All term infants with neurological abnormalities presenting in the first day of life were systematically examined and described according to a conventionally defined encephalopathy grading system. Major congenital malformations and neonatal infections were excluded. RESULTS: Over 12 months there were 14,771 total births of a weight of 500 g or more of which 14,371 were live births and 400 were stillbirths. Of 734 infants with 1 min Apgar of three or less, 91 developed NE. The positive and negative predictive values of 1 min Apgar of three or less for NE were 11.4% and 99.9%, respectively. The probability of developing NE rose from 0.6% (amongst all infants born at this hospital) to 11.2% (amongst infants born with a one minute Apgar of three or less). CONCLUSIONS: An Apgar score of 3 or less at one minute is a useful screening test for clinically significant birth asphyxia (NE). It overestimates by eight fold the scale of the birth asphyxia problem, but identifies a high risk group requiring further observation of their neurological condition.en_US
dc.description.affiliationCenter for International Child Health, Institute of Child Health, London, United Kingdom.en_US
dc.identifier.citationEllis M, Manandhar N, Manandhar DS, deL Costello AM. An Apgar score of three or less at one minute is not diagnostic of birth asphyxia but is a useful screening test for neonatal encephalopathy. Indian Pediatrics. 1998 May; 35(5): 415-21en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/9635
dc.language.isoengen_US
dc.source.urihttps://indianpediatrics.neten_US
dc.subject.meshApgar Scoreen_US
dc.subject.meshAsphyxia Neonatorum --classificationen_US
dc.subject.meshBias (Epidemiology)en_US
dc.subject.meshBirth Injuries --classificationen_US
dc.subject.meshBrain Injuries --classificationen_US
dc.subject.meshHumansen_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshNeonatal Screening --methodsen_US
dc.subject.meshReproducibility of Resultsen_US
dc.subject.meshSeverity of Illness Indexen_US
dc.subject.meshTime Factorsen_US
dc.titleAn Apgar score of three or less at one minute is not diagnostic of birth asphyxia but is a useful screening test for neonatal encephalopathy.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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