A study on lipid profile in thyroid dysfunction

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dc.contributor.authorD, BPen_US
dc.contributor.authorMaliekkal, Jen_US
dc.contributor.authorN, Gen_US
dc.contributor.authorH, ANV.en_US
dc.date.accessioned2023-06-27T06:43:03Z
dc.date.available2023-06-27T06:43:03Z
dc.date.issued2023-06
dc.description.abstractBackground: Thyroid diseases are among the most common endocrine disorders worldwide. Thyroid hormones play a key role in regulating the synthesis, metabolism, and mobilization of lipids. Levels of circulating lipids may alter in thyroid dysfunction. Aim and Objectives: The aim of the study was to find out the alterations of lipid levels in thyroid dysfunction. Materials and Methods: The study was designed as cross-sectional observational study and analysis of values was done by significant tests difference in means. 20 patients with hypothyroidism, 20 patients with hyperthyroidism, and 20 normal were participated in the study. Levels of total cholesterol, triglycerides, high density lipoprotein cholesterol (HDL-C), very low density lipoprotein cholesterol (VLDL-C), LDL-C, and LDL/HDL ratio were estimated and compared. Results: In patients with hypothyroidism, there was an increase in total cholesterol, LDL-C, and triglyceride levels and decrease in HDL-C levels. In hyperthyroidism, total cholesterol, triglycerides, LDL-C, VLDL-C, and LDL/HDL ratio were found to be significantly decreased. Conclusion: Altered thyroid function can lead to significant changes in the lipid profile. Hypothyroidism is an important risk factor for heart diseases. Hence, routine screening of thyroid hormones may be of considerable help for early intervention and treatment of thyroid dysfunction-related cardiac disease.en_US
dc.identifier.affiliationsDepartment of Physiology, Government Medical College, Kozhikode, Kerala, Indiaen_US
dc.identifier.citationD BP, Maliekkal J, N G, H ANV. . A study on lipid profile in thyroid dysfunction. National Journal of Physiology, Pharmacy and Pharmacology. 2023 Jun; 13(6): 1174-1178en_US
dc.identifier.issn2231-3206
dc.identifier.issn2320-4672
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/218128
dc.languageenen_US
dc.publisherMrs Dipika Charan of MedScience (India) Publicationsen_US
dc.relation.issuenumber6en_US
dc.relation.volume13en_US
dc.source.urihttps://dx.doi.org/10.5455/njppp.2023.13.11524202209112022en_US
dc.subjectThyroid Dysfunctionen_US
dc.subjectHypothyroidismen_US
dc.subjectHyperthyroidismen_US
dc.subjectLipid Profileen_US
dc.subjectTotal Cholesterolen_US
dc.subjectTriglyceridesen_US
dc.subjectHigh Density Lipoprotein-Cholesterolen_US
dc.subjectLow Density Lipoprotein-Cholesterolen_US
dc.subjectVery Low Density Lipoprotein Cholesterolen_US
dc.subjectLow Density Lipoprotein/High Density Lipoprotein Ratioen_US
dc.titleA study on lipid profile in thyroid dysfunctionen_US
dc.typeJournal Articleen_US
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