An Efficacy, Safety and Tolerability Study of Ferrous Ascorbate and Folic Acid (Phosfomin-XT) in Iron Deficiency Anemia.
| dc.contributor.author | Adsul, B B | |
| dc.contributor.author | Mukaddam, Qayum | |
| dc.contributor.author | Khandeparkar, Prashant | |
| dc.contributor.author | Naik, Manoj | |
| dc.date.accessioned | 2017-01-23T05:04:46Z | |
| dc.date.available | 2017-01-23T05:04:46Z | |
| dc.date.issued | 2012-04 | |
| dc.description.abstract | Aim: This study was aimed to assess efficacy, safety and tolerability of combination of ferrous ascorbate and folic acid (Phosfomin-XT) in patients with iron deficiency anemia (IDA). Settings and design: A total of 56 patients, who were between 18-55 years of age, with hemoglobin (Hb) 6-9 g/dl and serum ferritin <15 mg/l also complying with the inclusion and exclusion criteria in the protocol were enrolled in the study after obtaining necessary approvals and informed consent. All were dispensed with Phosfomin-XT fixed-dose combination (FDC) of ferrous ascorbate (equivalent to elemental iron 100 mg) + folic acid 1.5 mg tablet once-daily after food for eight weeks. Patients were assessed at baseline and Weeks 2, 4, 6 and 8 for change in Hb level, clinical evaluation and target Hb achievement. Results: Baseline mean Hb was 08.39 ± 0.75 g/dl, which significantly increased to 9.76 ± 0.70 g/dl (16.3%) at Week 2 and further increased to 10.70 ± 0.70 g/dl (27.53%) at Week 4. At Week 6, it increased to 11.55 ± 0.67 g/dl (37.7%) and at Week 8, it increased to 12.53 ± 1.09 g/dl. Conclusions: The present study concludes that Phosfomin-XT (ferrous ascorbate, equivalent to elemental iron 100 mg + folic acid 1.5 mg) tablet should be preferred as first choice of oral iron salts to treat IDA due to positive effect on Hb value and superior tolerability. | en_US |
| dc.identifier.citation | Adsul B B, Mukaddam Qayum, Khandeparkar Prashant, Naik Manoj. An Efficacy, Safety and Tolerability Study of Ferrous Ascorbate and Folic Acid (Phosfomin-XT) in Iron Deficiency Anemia. Indian Journal of Clinical Practice. 2012 Apr; 22(11): 565-570. | en_US |
| dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/182224 | |
| dc.language.iso | en | en_US |
| dc.source.uri | https://medind.nic.in/iaa/t12/i4/iaat12i4p565.pdf | en_US |
| dc.subject | Iron deficiency anemia | en_US |
| dc.subject | ferrous ascorbate | en_US |
| dc.subject | folic acid | en_US |
| dc.title | An Efficacy, Safety and Tolerability Study of Ferrous Ascorbate and Folic Acid (Phosfomin-XT) in Iron Deficiency Anemia. | en_US |
| dc.type | Article | en_US |