Infections in acute myeloid leukemia. Study of 184 febrile episodes.

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dc.contributor.authorKumar, Len_US
dc.contributor.authorKochupillai, Ven_US
dc.contributor.authorBhujwala, R Aen_US
dc.date.accessioned1992-01-01en_US
dc.date.accessioned2009-05-30T20:23:10Z
dc.date.available1992-01-01en_US
dc.date.available2009-05-30T20:23:10Z
dc.date.issued1992-01-01en_US
dc.description.abstractWe analysed the case records of 75 patients with acute myeloid leukaemia treated at our institute from January 1984 to December 1988 to see the pattern and severity of infections and their relationship with granulocytopenia. A total of 184 febrile episodes (mean 2.45) were recorded; 153 (83.15%) were associated with granulocytopenia while 31 (16.84%) were without granulocytopenia. Among granulocytopenic patients, infections could be documented microbiologically in 58.2% and clinically in 30.0% of episodes. In the remaining 41.8% of episodes, no clinical, radiological or microbiological evidence could be found out. The various sites of infection were: septicaemia 21 (13.72%), disseminated fungal infections 4 (2.6%), upper respiratory tract 21 (13.7%), chest 58 (37.9%), gastrointestinal tract 8 (5.2%), genitourinary (7.2%), soft tissues 5 (3.2%) and skin cellulitis 7 (4.6%). Microbiologically, gram negative organisms (Klebsiella pneumoniae, E coli, Pseudomonas aeruginosa) were most common, followed by gram positive (Streptococcal faecalis, Staphylococcus aureus, Staph albus, Staph epidermidis). Four patients had disseminated fungal infection: candida 2, aspergillus *1, mucormycosis *1. Among non neutropenic febrile episodes, the sites infected were: septicemia 2 (6.4%), chest 9(29.0%), upper respiratory tract 1 (3.2%), gastrointestinal 1 (3.2%), soft tissue 1 (3.2%), drug fever 3 (9.6%) and fever of unknown origin 14 (45.2%).en_US
dc.description.affiliationDepartment of Medical Oncology, Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi.en_US
dc.identifier.citationKumar L, Kochupillai V, Bhujwala RA. Infections in acute myeloid leukemia. Study of 184 febrile episodes. Journal of the Association of Physicians of India. 1992 Jan; 40(1): 18-20en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/87651
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshAcute Diseaseen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshBacterial Infections --complicationsen_US
dc.subject.meshFemaleen_US
dc.subject.meshFever --etiologyen_US
dc.subject.meshGram-Negative Bacterial Infections --complicationsen_US
dc.subject.meshHumansen_US
dc.subject.meshLeukemia, Myeloid --complicationsen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNeutropenia --complicationsen_US
dc.titleInfections in acute myeloid leukemia. Study of 184 febrile episodes.en_US
dc.typeJournal Articleen_US
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