Uterine blood flow response to hormonal replacement therapy in asymptomatic postmenopausal women: a transvaginal Doppler study.

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dc.contributor.authorTanawattanacharoen, Sen_US
dc.contributor.authorPanyakhamlerd, Ken_US
dc.contributor.authorChaikittisilpa, Sen_US
dc.contributor.authorTaechakraichana, Nen_US
dc.contributor.authorLimpaphayom, K Ken_US
dc.date.accessioned2009-05-27T20:35:58Z
dc.date.available2009-05-27T20:35:58Z
dc.date.issued2000-04-16en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractTo evaluate the effect of continuous hormonal replacement therapy (HRT) on Doppler parameters of uterine blood flow in asymptomatic postmenopausal women. Thirty-eight asymptomatic postmenopausal women were recruited into the study from the outpatient menopause clinic, Department of Obstetrics and Gynaecology, Faculty of Medicine, Chulalongkorn University. The study population was divided into 20 cases without any HRT (group 1) and 18 cases using continuous conjugated equine estrogen 0.625 mg/day combined with medroxyprogesterone acetate 2.5 mg/day (group 2). The duration of HRT was 21.3 +/- 9.5 (13-56) months. A transvaginal colour flow imaging system (ALOKA SSD-2000 MultiView, Tokyo, Japan) was used to assess uterine blood flow. Quantitative data from areas of colour were evaluated by pulsed Doppler spectrum analysis. Resistance indices (RI) were measured as indicators of uterine perfusion. Both groups were statistically similar with respect to age, parity, age at menopause, height and weight. The endometrial thickness in group 1 and 2 were 3.8 +/- 0.8 and 4.1 +/- 0.6 millimetres, respectively. The left uterine artery RIs of group 1 and 2 were 0.86 +/- 0.08 and 0.84 +/- 0.07, respectively (p = 0.33). The right uterine artery RIs of group 1 and 2 were 0.87 +/- 0.07 and 0.83 +/- 0.06, respectively (p = 0.06). In conclusion, continuous HRT had a non-significant influence on uterine blood flow in the postmenopausal women.en_US
dc.description.affiliationDepartment of Obstetrics and Gynaecology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.en_US
dc.identifier.citationTanawattanacharoen S, Panyakhamlerd K, Chaikittisilpa S, Taechakraichana N, Limpaphayom KK. Uterine blood flow response to hormonal replacement therapy in asymptomatic postmenopausal women: a transvaginal Doppler study. Journal of the Medical Association of Thailand. 2000 Apr; 83(4): 368-73en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/43290
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAgeden_US
dc.subject.meshBlood Flow Velocity --drug effectsen_US
dc.subject.meshEstrogen Replacement Therapyen_US
dc.subject.meshEstrogens, Conjugated (USP) --administration & dosageen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMedroxyprogesterone --administration & dosageen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPostmenopause --drug effectsen_US
dc.subject.meshProgesterone Congeners --administration & dosageen_US
dc.subject.meshReference Valuesen_US
dc.subject.meshSensitivity and Specificityen_US
dc.subject.meshUltrasonography, Doppler, Coloren_US
dc.subject.meshUterus --blood supplyen_US
dc.titleUterine blood flow response to hormonal replacement therapy in asymptomatic postmenopausal women: a transvaginal Doppler study.en_US
dc.typeClinical Trialen_US
dc.typeComparative Studyen_US
dc.typeControlled Clinical Trialen_US
dc.typeJournal Articleen_US
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