Evaluation of safety and efficacy of ketoconazole 2% and zinc pyrithione 1% shampoo in patients with moderate to severe dandruff--a postmarketing study.

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dc.contributor.authorSaple, D Gen_US
dc.contributor.authorRavichandran, Gen_US
dc.contributor.authorDesai, Aen_US
dc.date.accessioned2000-12-08en_US
dc.date.accessioned2009-05-31T09:57:24Z
dc.date.available2000-12-08en_US
dc.date.available2009-05-31T09:57:24Z
dc.date.issued2000-12-08en_US
dc.description.abstractA postmarketing study was conducted on 236 patients from 23 centres suffering from moderate to severe dandruff with a combination of ketoconazole and zinc pyrithione (1%) for a duration of 4 weeks with 2 weeks further follow-up. Scoring of dandruff was done on a 0-10 scale for each of the 6 regions of scalp at each week up to 6 weeks. The results indicate that there was a consistent improvement in dandruff scores over the treatment period and a reduction of > 90% was seen for all areas of scalp individually as well as collectively as compared to baseline. The treatment also showed significant improvement in other signs and symptoms such as erythema and itching, with a highly favourable adverse event profile. The overall assessment for global improvement by investigators showed good-excellent results with high acceptability amongst the patient population for the treatment. A combination shampoo of ketoconazole (2%) and zinc pyrithione (1%) offers a safe and effective option in the treatment of dandruff.en_US
dc.description.affiliationSTDs, Leprosy and AIDS Medicine, Grant Medical College, GT Hospital, Mumbai.en_US
dc.identifier.citationSaple DG, Ravichandran G, Desai A. Evaluation of safety and efficacy of ketoconazole 2% and zinc pyrithione 1% shampoo in patients with moderate to severe dandruff--a postmarketing study. Journal of the Indian Medical Association. 2000 Dec; 98(12): 810-1en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/98997
dc.language.isoengen_US
dc.source.urihttps://www.jimaonline.org.in/en_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAntifungal Agents --therapeutic useen_US
dc.subject.meshFemaleen_US
dc.subject.meshHair Preparations --chemistryen_US
dc.subject.meshHumansen_US
dc.subject.meshKetoconazole --therapeutic useen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshOrganometallic Compounds --therapeutic useen_US
dc.subject.meshPyridines --therapeutic useen_US
dc.subject.meshScalp Dermatoses --drug therapyen_US
dc.subject.meshZinc --therapeutic useen_US
dc.titleEvaluation of safety and efficacy of ketoconazole 2% and zinc pyrithione 1% shampoo in patients with moderate to severe dandruff--a postmarketing study.en_US
dc.typeEvaluation Studiesen_US
dc.typeJournal Articleen_US
dc.typeMulticenter Studyen_US
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