Infective endocarditis: prevalence, characteristics and mortality in Khon Kaen, 1990-1999.

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dc.contributor.authorPachirat, Orathaien_US
dc.contributor.authorChetchotisakd, Ploenchanen_US
dc.contributor.authorKlungboonkrong, Viraten_US
dc.contributor.authorTaweesangsuksakul, Prawiten_US
dc.contributor.authorTantisirin, Cherdchaien_US
dc.contributor.authorLoapiboon, Malineeen_US
dc.date.accessioned2009-05-27T21:12:06Z
dc.date.available2009-05-27T21:12:06Z
dc.date.issued2002-01-22en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractOBJECTIVE: To update the prevalence, characteristics and mortality of infective endocarditis in a tertiary care hospital in Khon Kaen, Thailand. BACKGROUND: Numerous studies have shown that the prevalence and course of infective endocarditis remain unchanged inspite of the advance in treatment, diagnosis and of prophylactic recommendations. METHOD: The authors identified 160 patients from 1990-1999 with 86 per cent definite and 14 per cent possible endocarditis based on the Duke criteria. Data were collected from two tertiary care hospitals. RESULTS: The prevalence was 4 patients per 1,000 hospital admissions. The mean age of the 106 male and 54 female patients was 39+/-16 years. Twenty-four percent of the patients had no previously known heart disease. Native valve endocarditis was present in 95 per cent and prosthetic valve endocarditis was diagnosed in 5 per cent. Infective endocarditis was located on the aortic valve in 42 per cent, the mitral valve in 43 per cent, both mitral and aortic valves in 9 per cent and the tricuspid valve in 8 per cent. The infective organism was identified in only 62 per cent of cases. Streptococci was the most common in 43 per cent, followed by Staphylococci in 16 per cent. During the first month after admission, 45 per cent of the patients underwent surgery. In-hospital mortality was 25 per cent. CONCLUSION: Despite improved diagnostic techniques and aggressive surgical therapy, infective endocarditis remains a serious problem associated with a high mortality in Khon Kaen.en_US
dc.description.affiliationDivision of Cardiovascular Disease and Internal Medicine, Khon Kaen University, Thailand.en_US
dc.identifier.citationPachirat O, Chetchotisakd P, Klungboonkrong V, Taweesangsuksakul P, Tantisirin C, Loapiboon M. Infective endocarditis: prevalence, characteristics and mortality in Khon Kaen, 1990-1999. Journal of the Medical Association of Thailand. 2002 Jan; 85(1): 1-10en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/44374
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAdulten_US
dc.subject.meshAge Distributionen_US
dc.subject.meshAnti-Bacterial Agents --administration & dosageen_US
dc.subject.meshCohort Studiesen_US
dc.subject.meshEndocarditis, Bacterial --diagnosisen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPrevalenceen_US
dc.subject.meshPrognosisen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshRisk Assessmenten_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSex Distributionen_US
dc.subject.meshStreptococcal Infections --diagnosisen_US
dc.subject.meshSurvival Rateen_US
dc.subject.meshThailand --epidemiologyen_US
dc.titleInfective endocarditis: prevalence, characteristics and mortality in Khon Kaen, 1990-1999.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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