Prevalence, species distribution and antifungal sensitivity of vaginal yeasts in infertile women.
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2001-07-25
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A total of 326 high vaginal swabs from infertile women attending the Institute of Reproductive Medicine were cultured from June 1999 to May 2000. Candida species was isolated from 42(12.88%) patients. Candida albicans (40.47%) followed by Candida glabrata (38.09%) were the most common isolates. Other species included Candida tropicalis (14.28%) and Candida krusei (7.14%). All isolates were tested for sensitivity by disc diffusion method on Yeast Nitrogen Agar base towards four antifungals. Seven (16.7%) candida strains showed resistance to Fluconazole and 19(45.23%) of the strains showed resistance to Itraconazole, and 4(9.5%) strains showed resistance to Nystatin. There was no resistance to Amphotericin B. Of the 7 strains resistant to Fluconazole, 3 were Candida krusei, 3 were Candida glabrata and 1 was Candida tropicalis.
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Verghese S, Padmaja P, Asha M, Elizabeth SJ, Anitha A, Kundavi KM, Jayanthi N, Varma T. Prevalence, species distribution and antifungal sensitivity of vaginal yeasts in infertile women. Indian Journal of Pathology & Microbiology. 2001 Jul; 44(3): 313-4