Antibiogram of Gram Negative Uropathogens in a Tertiary Care Hospital

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dc.contributor.authorDavane, Milinden_US
dc.contributor.authorMundhe, Sanjivanien_US
dc.date.accessioned2023-07-14T07:55:12Z
dc.date.available2023-07-14T07:55:12Z
dc.date.issued2021-06
dc.description.abstractBackground:In wide range, urinary tract infection (UTI) is a substantial and second most popular bacterial infection affecting individuals of overall ages worldwide. The chronicity of divergent bacterial isolates and their propensity to various antibiotics may contradict widely, peculiarly in hospitalized patients, this makes the survey of vulnerability pattern extremely mandatory for correct selection of antibiotics. Objective: To appraise antimicrobial susceptibility pattern of the Gram negative organisms identified from urine cultures of hospitalized patients. Methodology:Total 500 urine samples from hospitalized patients with significant bacteriuria were surveyed. Using Blood and MacConckey agar, samples were inoculated. Further identification and investigation of organisms was done by standard Microbiological methods. Antimicrobial Susceptibility pattern was interpreted by Modified Kirby- Bauer's disc diffusion method with the group of 15 drugs as per Clinical Laboratories Standard Institute (CLSI) protocols.Results:UTIs were frequent in females 290 (58%). Familiar organism found was Escherichia coli 260 (52%) further accompanied by Klebsiellaspp.120 (24%), Pseudomonas spp.40 (8%), Proteus spp. 38 (7.6%), Citrobacter spp.25(5%) and Acinetobacterspp. 17 (3.4%). Mass of the strains were found sensitive to nitrofurantoin followed by amikacin, piperacillin-tazobactamand cotrimoxazole. Commonly prescribed fluroquinolones were found least effective for treatment of UTI. All the strains were found sensitive to imipenem. Extended spectrum beta lactamase (ESBL) was noted in E.coli and in Klebsiella spp.Conclusion:To break the continuity of non selective use of antibiotics and to intercept further development of bacterial drug resistance, proper knowledge of susceptibility pattern of uropathogens in particular area is very important before prescribing any empirical antibiotic therapyen_US
dc.identifier.affiliationsAssistant Professor, Department of Microbiology, MIMSR Medical College& Hospital, Latur-413531, Maharashtra, Indiaen_US
dc.identifier.citationDavane Milind, Mundhe Sanjivani. Antibiogram of Gram Negative Uropathogens in a Tertiary Care Hospital. VIMS Health Science Journal. 2021 Jun; 8(2): 80-84en_US
dc.identifier.issn2348-523X
dc.identifier.issn2454-1982
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/219046
dc.languageenen_US
dc.publisherDr. Vithalrao Vikhe Patil Foundation Ahmednagaren_US
dc.relation.issuenumber2en_US
dc.relation.volume8en_US
dc.source.urihttps://doi.org/10.46858/vimshsj.8207en_US
dc.subjectAntimicrobial sensitivityen_US
dc.subjectGram negative bacteriaen_US
dc.subjectUrinary tract infection (UTI)en_US
dc.subjectHospitalized patientsen_US
dc.titleAntibiogram of Gram Negative Uropathogens in a Tertiary Care Hospitalen_US
dc.typeJournal Articleen_US
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