Atrial fibrillation: epidemiology, mechanisms and management.

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dc.contributor.authorBhatia, Aen_US
dc.contributor.authorSra, Jen_US
dc.date.accessioned2000-03-14en_US
dc.date.accessioned2009-05-27T04:22:16Z
dc.date.available2000-03-14en_US
dc.date.available2009-05-27T04:22:16Z
dc.date.issued2000-03-14en_US
dc.description284 references.en_US
dc.description.abstractThe incidence of AF, the most common sustained arrhythmia in clinical practice, increases with age and coronary artery disease, hypertension and valvular heart disease are common underlying substrates; however, occasionally, AF may occur without any underlying heart disease. The most widely accepted theory of its mechanism is Moe's multiple wavelet hypothesis, although recent studies are helping to shed light on other mechanisms, including the focal origin of AF in some patients. Most patients experience palpitations, but fatigue, dyspnoea, and dizziness may also occur. Therapy includes prevention of thromboembolism, control of rate, and restoration and maintenance of sinus rhythm. The risks and benefits of each treatment modality need to be assessed according to each patient's circumstances. Unlike other arrhythmias, there is still no highly successful therapy for treating AF. However, significant advances are being made using non-pharmacological approaches to either prevent or cure this troublesome arrhythmia.en_US
dc.description.affiliationElectrophysiology Laboratories, St Luke's Medical Centre, University of Wisconsin Medical School, Milwaukee, USA.en_US
dc.identifier.citationBhatia A, Sra J. Atrial fibrillation: epidemiology, mechanisms and management. Indian Heart Journal. 2000 Mar-Apr; 52(2): 129-64en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/4234
dc.language.isoengen_US
dc.source.urihttps://indianheartjournal.comen_US
dc.subject.meshAmiodarone --therapeutic useen_US
dc.subject.meshAnti-Arrhythmia Agents --therapeutic useen_US
dc.subject.meshAnticoagulants --therapeutic useen_US
dc.subject.meshAtrial Fibrillation --drug therapyen_US
dc.subject.meshClinical Trials as Topicen_US
dc.subject.meshDefibrillators, Implantableen_US
dc.subject.meshHumansen_US
dc.subject.meshPrognosisen_US
dc.subject.meshRisk Assessmenten_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSportsen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleAtrial fibrillation: epidemiology, mechanisms and management.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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