Evaluation of anaphylactic reaction as an adverse event for perindopril erbumine tablets.

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dc.contributor.authorKrishnan, Kiran
dc.contributor.authorKrishnasamy, Kathiresan
dc.date.accessioned2014-07-24T09:36:13Z
dc.date.available2014-07-24T09:36:13Z
dc.date.issued2013-03
dc.description.abstractPerindopril erbumine is a tert-butylamine salt of perindopril used in the treatment of stable coronary artery disease and hyperten-sion. The present study was aimed to evaluate the anaphylactic reaction as an adverse event for perindopril erbumine tablets. Electronic extraction of data from the safety database for this report includes all cases of anaphylactic reaction where perindopril was a primary or co-suspect drug. The study result have shown that there were overall 205 case reports for perindopril in the database, of which 200 cases were assessed as (potentially) perindopril and 05 were assessed as non-perindopril product. From the 200 case reports, 141 were serious and 59 were non-serious. Out of the 141 serious cases, 137 cases were medically confirmed while remaining 04 cases were consumer reports. Of the total 205 case reports there were five cases wherein the patient experienced anaphylactic reaction. The study concludes that three out of five cases entered in the drug safety database suggestive of a possible association between perindopril and anaphylactic reaction.en_US
dc.identifier.citationKrishnan Kiran, Krishnasamy Kathiresan. Evaluation of anaphylactic reaction as an adverse event for perindopril erbumine tablets. International Current Pharmaceutical Journal. 2014 Mar 3(4): 254-258.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/153086
dc.language.isoenen_US
dc.source.urihttps://www.icpjonline.com/documents/Vol3Issue4/02Abstract.htmen_US
dc.subjectAngiotensin-converting enzymeen_US
dc.subjectcoronary artery diseaseen_US
dc.subjecthypertensionen_US
dc.subjectperindoprilaten_US
dc.subjectsystem organ classen_US
dc.subjecttert-butylamine salten_US
dc.titleEvaluation of anaphylactic reaction as an adverse event for perindopril erbumine tablets.en_US
dc.typeArticleen_US
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