Multilayered inverted internal limiting membrane flap technique versus standard internal limiting membrane peeling for large macular holes: A comparative study

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dc.contributor.authorBelenje, Akashen_US
dc.contributor.authorTakkar, Brijeshen_US
dc.contributor.authorAgarwal, Komalen_US
dc.contributor.authorTyagi, Muditen_US
dc.contributor.authorAggarwal, Vinoden_US
dc.contributor.authorPadhi, Tapas Ren_US
dc.contributor.authorNarayanan, Rajaen_US
dc.date.accessioned2023-08-25T06:32:20Z
dc.date.available2023-08-25T06:32:20Z
dc.date.issued2022-03
dc.description.abstractPurpose: To evaluate the outcome of vitrectomy with multilayered inverted internal limiting membrane flap technique (ML?IILM) versus vitrectomy with standard ILM peeling for large macular holes in terms of visual acuity and anatomical closure. Methods: A hospital?based, prospective, randomized, interventional study was conducted during three calendar years with a total 150 eyes (75 in each group) in two groups—vitrectomy with ILM peeling (Group A) and vitrectomy with ML?IILM flap technique (Group B) after informed consent of study participants who met the inclusion criteria. Results: The mean minimum and maximum diameter of macular hole did not differ statistically in both the groups. Macular hole index had no significant difference between both groups Pre?operative visual acuity was not statistically significantly different between the two groups. During follow?up, best corrected visual acuity (BCVA) at 1 month, 3 months, 6 months, and 12 months was significantly better in Group B (0.12 ± 0.07 at 1 month, 0.14 ± 0.10 at 3 months, 0.18 ± 0.11 at 6 months, and 0.19 ± 0.12 at 12 months) compared to Group A (0.20 ± 0.11 at 1 month, 0.22 ± 0.13 at 3 months, 0.30 ± 0.12 at 6 months, and 0.31 ± 0.14 at 12 months) (P = 0.001 for each). Type 1 anatomical closure (flattening of cuff and opposition of edges of hole) was achieved in 78.66% (59/75) cases in Group A and 93.33% (70/75) cases in Group B (P 0.0016). Conclusion: Vitrectomy with multilayered inverted ILM flap technique had significantly higher anatomical closure and better visual outcome than vitrectomy with standard ILM peelingen_US
dc.identifier.affiliationsDepartment of Ophthalmology, SMS Medical College, Jaipur, Rajasthan, Indiaen_US
dc.identifier.affiliationsDepartment of Ophthalmology, AIIMS, Jodhpur, Rajasthan, Indiaen_US
dc.identifier.citationBelenje Akash, Takkar Brijesh, Agarwal Komal, Tyagi Mudit, Aggarwal Vinod, Padhi Tapas R, Narayanan Raja. Multilayered inverted internal limiting membrane flap technique versus standard internal limiting membrane peeling for large macular holes: A comparative study. Indian Journal of Ophthalmology. 2022 Mar; 70(3): 909-913en_US
dc.identifier.issn1998-3689
dc.identifier.issn0301-4738
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/224192
dc.languageenen_US
dc.publisherAll India Ophthalmological Societyen_US
dc.relation.issuenumber3en_US
dc.relation.volume70en_US
dc.source.urihttps://doi.org/10.4103/ijo.IJO_1530_21en_US
dc.subjectAnatomical closureen_US
dc.subjectILM flapen_US
dc.subjectILM peelingen_US
dc.subjectlarge macular holeen_US
dc.subjectvitrectomyen_US
dc.subjectvisual acuityen_US
dc.titleMultilayered inverted internal limiting membrane flap technique versus standard internal limiting membrane peeling for large macular holes: A comparative studyen_US
dc.typeJournal Articleen_US
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