Morphine-induced modulation of sciatic nerve stimulation evoked blood pressure responses.

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dc.contributor.authorBhattacharya, Nen_US
dc.contributor.authorMahajan, Sen_US
dc.contributor.authorSharma, K Nen_US
dc.date.accessioned1991-04-01en_US
dc.date.accessioned2009-06-01T07:54:05Z
dc.date.available1991-04-01en_US
dc.date.available2009-06-01T07:54:05Z
dc.date.issued1991-04-01en_US
dc.description.abstractEffect of i.v. morphine (1-2 mg/kg) on blood pressure changes evoked by sciatic nerve stimulation (SNS) were studied in chloralose anaesthetised cats. SNS gave a depressor, pressor or a biphasic BP response generally linked to the parameters of stimulation. Morphine produced marked attenuation of depressor and some facilitation of pressor response, suggesting a possible reciprocal relationship between depressor and pressor responses. Depressor response has been correlated with deep tissue or visceral pain mediated through A delta fibres and pressor response to cutaneous nociception involving C fibres or non nociceptive input via group II fibres. Involvement of medullary regions in differential modulation of these depressor and pressor response has been suggested.en_US
dc.description.affiliationDepartment of Physiology, University College of Medical Sciences, Shahdara, Delhi.en_US
dc.identifier.citationBhattacharya N, Mahajan S, Sharma KN. Morphine-induced modulation of sciatic nerve stimulation evoked blood pressure responses. Indian Journal of Physiology and Pharmacology. 1991 Apr; 35(2): 125-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/108508
dc.language.isoengen_US
dc.source.urihttps://www.ijpp.comen_US
dc.subject.meshAnesthesiaen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBlood Pressure --drug effectsen_US
dc.subject.meshCatsen_US
dc.subject.meshMorphine --pharmacologyen_US
dc.subject.meshNociceptors --drug effectsen_US
dc.subject.meshSciatic Nerve --drug effectsen_US
dc.titleMorphine-induced modulation of sciatic nerve stimulation evoked blood pressure responses.en_US
dc.typeJournal Articleen_US
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