Mycophenolate mofetil-induced colitis with graft versus host disease-like features in a liver transplant recipient.
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Date
2012-10
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Abstract
Mycophenolate mofetil (MMF) is a commonly used immunosuppressive drug in the management of transplant recipients. Gastrointestinal (GI) toxicity (diarrhea) is the most frequently reported adverse event in MMF-treated transplant patients. MMF-induced Graft versus Host Disease has rarely been reported in literature. We report a case of MMF-induced colitis with Graft versus Host Disease-like features, to highlight the importance of high clinical suspicion for its diagnosis, and that appropriate management in such a setting can reduce morbidity and mortality. We also review the relevant literature.
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Keywords
Gastrointestinal toxicity, liver transplant, mycophenolate mofetil, MMF-induced colitis, graft versus host disease-like features
Citation
Patra Sushma, Vij Mukul, Sukanya B, Kapoor Dharmesh. Mycophenolate mofetil-induced colitis with graft versus host disease-like features in a liver transplant recipient. Indian Journal of Pathology & Microbiology. 2012 Oct-Dec 55(4): 506-508.