Hepatocellular carcinoma presenting as neutrophilic leukaemoid reaction--a rare entity.

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Date
2007-08-02
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Abstract
Leukaemoid reaction is a rare, growth factor-driven, paraneoplastic manifestation of hepatocellular carcinoma. It may masquerade as the neutrophilic chronic myeloid leukaemia or as chronic neutrophilic leukaemia. A 52-year-old male presented with hepatosplenomegaly and severe leucocytosis. He had progressive leucocytosis, neutrophil alkaline phosphatase score elevated, liver function tests altered. FNAC from the mass in the liver revealed features of moderately differentiated hepatocellular carcinoma. The patient deteriorated within two weeks and died thereafter.
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Tilak V, Rai M, Singh VP, Rai AK, Raman R. Hepatocellular carcinoma presenting as neutrophilic leukaemoid reaction--a rare entity. Journal of the Indian Medical Association. 2007 Aug; 105(8): 462, 464-5
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https://imsear.searo.who.int/handle/123456789/98545
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Journal of the Indian Medical Association