Effect of feeding high fat, high fiber diet on brush border enzymes in mice intestine.

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dc.contributor.authorGupta, Ren_US
dc.contributor.authorJaswal, V Men_US
dc.contributor.authorKaur, Jen_US
dc.contributor.authorMahmood, Aen_US
dc.date.accessioned1993-06-01en_US
dc.date.accessioned2009-05-27T08:03:53Z
dc.date.available1993-06-01en_US
dc.date.available2009-05-27T08:03:53Z
dc.date.issued1993-06-01en_US
dc.description.abstractThe effect of dietary fat content on brush border enzymes has been studied in mice intestine. The results obtained from 26 per cent fat (high fat; HF)-fed mice were compared with those fed 10 per cent fat (pair-fed; PF and ad libitum-fed). Brush border alkaline phosphatase (AP), leucineaminopeptidase (LAP) and gamma-glutamyltranspeptidase (gamma-GTP) activities were significantly enhanced while sucrase activity was reduced (P < 0.001) in HF group compared to the controls. Activities of lactase, p-nitrophenyl (PNP)-beta-D-glucosidase and PNP-beta-D-galactosidase were unaltered under these conditions. Kinetic studies with AP, sucrase and LAP revealed that changes in enzyme levels in response to HF diet were due to change in Vmax. Significant changes in enzyme activities as a consequence of HF intake were observed in enterocytes all along the crypt-villus unit as compared to the control group. These results indicated that feeding a fat-rich diet produced selective changes in brush border enzyme activities in mice intestine.en_US
dc.description.affiliationDepartment of Biochemistry, Panjab University, Chandigarh.en_US
dc.identifier.citationGupta R, Jaswal VM, Kaur J, Mahmood A. Effect of feeding high fat, high fiber diet on brush border enzymes in mice intestine. Indian Journal of Medical Research. 1993 Jun; 98(): 136-42en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/23107
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshAnimalsen_US
dc.subject.meshDietary Fats --administration & dosageen_US
dc.subject.meshDietary Fiberen_US
dc.subject.meshIntestines --enzymologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiceen_US
dc.subject.meshMicrovilli --enzymologyen_US
dc.titleEffect of feeding high fat, high fiber diet on brush border enzymes in mice intestine.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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