Acute viral hepatitis in children: a prospective hospital based study

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dc.contributor.authorSharma, Chandra Madhuren_US
dc.contributor.authorGupta, Sanjayen_US
dc.contributor.authorAggarwal, Binduen_US
dc.contributor.authorChaudhary, Piyushen_US
dc.date.accessioned2020-09-24T07:48:53Z
dc.date.available2020-09-24T07:48:53Z
dc.date.issued2020-08
dc.description.abstractBackground: Viral hepatitis is a major public health issue throughout the world affecting millions of children despite the availability of vaccines, prophylactic measures and improved sanitation. The objective of the study was to analyze the etiology, clinical features, laboratory parameters and sonological findings of Acute Viral Hepatitis in pediatric population.Methods: A total of 88 children admitted in paediatric department and gastroenterology unit of medicine department with confirmed acute viral hepatitis from June 2016 to July 2018 at tertiary health care teaching hospital of north India were included. The patients were divided in 3 age groups; 1-5, 6-10 and 11-18 years. Clinical features, laboratory parameters, ultrasound findings were compared in three age groups.Results: Out of 88 cases 48 were boys and 40 girls. In the present study hepatitis A was the most common (85.2%) etiology. Jaundice (90.9%) is the most common symptoms followed by dark colored urine (86.3%), loss of appetite (83.3%) and fever (68.2%) reported in this study. Icterus (90%) is the most common sign reported followed by hepatomegaly (86%). Out of 88 cases 4 cases died. Out of 4 deaths, 2 cases of hepatitis A and 2 cases positive for Hepatitis B. The cause of death was hepatic encephalopathy in both the cases.Conclusions: Majority of cases in children were hepatitis A cases. Most of the cases were aged above 5 years with slight male predominance. Those cases with elevated liver enzymes (SGOT >5000) and those with PT INR >3.5 at admission has higher mortality.en_US
dc.identifier.affiliationsDepartment of Pediatrics, SGRR Institute of Medical and Health Sciences, Dehradun, Uttarakhand, Indiaen_US
dc.identifier.affiliationsDepartment of Gastroenterology, SGRR Institute of Medical and Health Sciences, Dehradun, Uttarakhand, Indiaen_US
dc.identifier.citationSharma Chandra Madhur, Gupta Sanjay, Aggarwal Bindu, Chaudhary Piyush. Acute viral hepatitis in children: a prospective hospital based study. International Journal of Contemporary Pediatrics. 2020 Aug; 7(8): 1681-1685en_US
dc.identifier.issn2349-3283
dc.identifier.issn2349-3291
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/204740
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber8en_US
dc.relation.volume7en_US
dc.source.urihttps://dx.doi.org/10.18203/2349-3291.ijcp20203039en_US
dc.subjectChildrenen_US
dc.subjectClinical profileen_US
dc.subjectHepatotropicen_US
dc.subjectViral hepatitisen_US
dc.titleAcute viral hepatitis in children: a prospective hospital based studyen_US
dc.typeJournal Articleen_US
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