Keratomycosis due to Purpureocillium lilacinum: A case report from Sub-Himalayan region of Uttarakhand

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Date
2018-12
Journal Title
Journal ISSN
Volume Title
Publisher
Indian Association of Pathologists and Microbiologists
Abstract
The fungus Purpureocillium lilacinum previously known as Paceliomyces lilacinus is an emerging pathogen that can cause severe human infections including devastating oculomycosis. Treatment with traditional antifungals often fails, and the organism shows variable susceptibility to novel triazoles. We hereby report a case of keratomycosis caused by Pur. lilacinum in an immunocompetent male patient following trauma. The patient was successfully treated with voriconazole. The drug shows good activity against Pur. lilacinum and could be a promising therapeutic alternative to treat infections caused by this fungus, which generally shows resistance to conventional antifungal agents including novel triazoles.
Description
Keywords
Keratitis, oculomycosis, Paecilomyces, Purpureocillium, voriconazole
Citation
Juyal D, Pal S, Sharma M, Negi V, Adekhandi S, Tyagi M. Keratomycosis due to Purpureocillium lilacinum: A case report from Sub-Himalayan region of Uttarakhand. Indian Journal of Pathology and Microbiology. 2018 Dec; 61(4): 607-609